溴哌利多

更新时间：2024-01-01 19:44:10

溴哌利多结构式	常用名	溴哌利多	英文名	Bromperidol
	CAS号	10457-90-6	分子量	420.31500
	密度	1.366 g/cm3	沸点	543.6ºC at 760 mmHg
	分子式	C₂₁H₂₃BrFNO₂	熔点	156-158ºC
	MSDS	N/A	闪点	282.6ºC
	符号	GHS07	信号词	Warning

溴哌利多用途

Bromperidol是一种丁酰苯类衍生物,是一种强效且长效的抗精神病药,用于治疗精神分裂症。

中文名	溴哌利多
英文名	Bromperidol
中文别名	溴哌醇
英文别名	更多

描述	Bromperidol是一种丁酰苯类衍生物,是一种强效且长效的抗精神病药,用于治疗精神分裂症。
相关类别	信号通路 >> G 蛋白偶联受体/G 蛋白 >> 5-HT受体信号通路 >> 神经信号通路 >> 5-HT受体研究领域 >> 神经疾病

密度	1.366 g/cm3
沸点	543.6ºC at 760 mmHg
熔点	156-158ºC
分子式	C₂₁H₂₃BrFNO₂
分子量	420.31500
闪点	282.6ºC
精确质量	419.09000
PSA	40.54000
LogP	4.47260
外观性状	黄褐色固体
蒸汽压	1.19E-12mmHg at 25°C
折射率	1.59
储存条件	库房通风低温干燥,与食品原料类分开存放
水溶解性	H2O: insoluble

溴哌利多毒性英文版

符号	GHS07
信号词	Warning
危害声明	H302
警示性声明	P301 + P312 + P330
危害码 (欧洲)	Xn
风险声明 (欧洲)	22
危险品运输编码	NONH for all modes of transport
WGK德国	3
RTECS号	EU1180000
海关编码	2933399090

4-[4-hydroxy-4-...

114361-10-3

~58%

溴哌利多

10457-90-6

文献：Vincent; Shambhu; Digenis Journal of medicinal chemistry, 1980 , vol. 23, # 1 p. 75 - 79

4-<4-<4-(trimet...

97042-48-3

~78%

溴哌利多

10457-90-6

文献：Moerlein, Stephen M.; Stoecklin, Gerhard L. Journal of Medicinal Chemistry, 1985 , vol. 28, # 9 p. 1319 - 1324

溴哌利多上游产品 1
CAS号114361-10-3 4-[4-hydroxy-4-...
溴哌利多下游产品 1
CAS号366-77-8 3-(4-氟苯甲酰)丙酸

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Simple and sensitive screening and quantitative determination of 88 psychoactive drugs and their metabolites in blood through LC–MS/MS: Application on postmortem samples

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 970 , 1-7, (2014)

• The introduction has been modified. • More references have been added to the text. • Limitations of the method have been discussed more in detail.

Sensitive determination of 4-(4-bromophenyl)-4-hydroxypiperidine, a metabolite of bromperidol, in rat plasma by HPLC with fluorescence detection after pre-column derivatization using 4-fluoro-7-nitro-2,1,3-benzoxadiazole.

Biol. Pharm. Bull. 29(12) , 2479-82, (2006)

The purpose of this study was to determine the level of 4-(4-bromophenyl)-4-hydroxypiperidine (BPHP), a bromperidol (BRO) metabolite, in rat plasma by HPLC with fluorescence detection after pre-column...

Folie à deux: double case-report of shared delusions with a fatal outcome.

Clin. Ter. 162(1) , 45-9, (2011)

Treatment of shared delusional disorder (folie à deux) often involves separation and use of antipsychotic medication, with uncertain outcomes and potential risks.We report on two highly interdependent...

MFCD00866670

4-(4-(4-Bromophenyl)-4-hydroxypiperidin-1-yl)-1-(4-fluorophenyl)butan-1-one

EINECS 233-943-3

4-[4-(4-bromophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one