Temocapril HCl

• 常用名: Temocapril HCl
• 英文名: Temocapril (hydrochloride)
• CAS号: 110221-44-8
• 分子量: 513.07
• 密度: N/A
• 沸点: 717.4ºC at 760 mmHg
• 分子式: C₂₃H₂₉ClN₂O₅S₂
• 熔点: 196-200ºC (dec)
• 闪点: 387.7ºC

Temocapril HCl用途

Temocapril盐酸盐是长效血管紧张素转换酶(ACE)抑制剂,可作用于高血压。

Temocapril HCl名称

• 中文名: 盐酸替莫普利
• 英文名: temocapril hydrochloride
• 中文别名: [(2S,6R)-6-[[(S)-1-(乙氧羰基)-3-苯基丙基]氨基]-5-氧代-2-(2-噻吩基)-1,4-硫氮杂卓-4-基]乙酸盐酸盐 | 替莫普利盐酸盐

Temocapril HCl生物活性

• 描述: Temocapril盐酸盐是长效血管紧张素转换酶(ACE)抑制剂,可作用于高血压。
• 相关类别:
  信号通路 >> 代谢酶/蛋白酶 >> 血管紧张素转换酶(ACE)
  研究领域 >> 心血管疾病
• 参考文献:

  [1]. Nakashima, M., et al., Pharmacokinetics of temocapril hydrochloride, a novel angiotensin converting enzyme inhibitor, in renal insufficiency. Eur J Clin Pharmacol, 1992. 43(6): p. 657-9.

  [2]. Furuta, S., et al., Pharmacokinetics of temocapril, an ACE inhibitor with preferential biliary excretion, in patients with impaired liver function. Eur J Clin Pharmacol, 1993. 44(4): p. 383-5.

Temocapril HCl物理化学性质

• 沸点: 717.4ºC at 760 mmHg
• 熔点: 196-200ºC (dec)
• 分子式: C₂₃H₂₉ClN₂O₅S₂
• 分子量: 513.07
• 闪点: 387.7ºC
• PSA: 153.42000
• LogP: 1.28460
• 外观性状: 白色固体粉末
• 蒸汽压: 1.34E-21mmHg at 25°C
• 折射率: 1.628
• 储存条件: -20°C Freezer

Temocapril HCl毒性和生态

Temocapril HCl安全信息

• 危害码 (欧洲): Xi
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): 26-36
• 海关编码: 2934999090

Temocapril HCl海关

• 海关编码: 2934999090
• 中文概述: 2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途
• Summary: 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Temocapril HCl英文别名

• Temocapril (hydrochloride)
• [(2S,6R)-6-{[(2S)-1-Ethoxy-1-oxo-4-phenyl-2-butanyl]amino}-5-oxo-2-(2-thienyl)-1,4-thiazepan-4-yl]acetic acid hydrochloride (1:1)
• CS-622
• [(2S,6R)-6-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-5-oxo-2-(2-thienyl)-1,4-thiazepan-4-yl]acetic acid hydrochloride
• [(2S,6R)-6-{[(2S)-1-Ethoxy-1-oxo-4-phenyl-2-butanyl]amino}-5-oxo-2-(2-thienyl)-1,4-thiazepan-4-yl]acetic acid hydrochloride
• (+)-(2S,6R)-6-(((1S)-1-Carboxy-3-phenylpropyl)amino)tetrahydro-5-oxo-2-(2-thienyl)-1,4-thiazepine-4(5H)-acetic acid 6-ethyl ester monohydrochloride
• [(2S,6R)-6-{[(2S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-5-oxo-2-(thiophen-2-yl)-1,4-thiazepan-4-yl]acetic acid hydrochloride
• 1,4-Thiazepine-4(5H)-acetic acid, 6-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-, (2S,6R)-, hydrochloride (1:1)
• Acecol
• Temocapril HCl
• Temocarpilhydrochloride
• TemocarpileHCL
• MFCD00933433
• [(2S,6R)-6-{[(2S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-5-oxo-2-(2-thienyl)-1,4-thiazepan-4-yl]acetic acid hydrochloride (1:1)
• (2S-(2a,6b(R*)))-6-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)tetrahydro-5-oxo-2-(2-thienyl)-1,4-thiazepine-4-(5H)-acetic acid monohydrochloride
• [(2S,6R)-6-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-5-oxo-2-(thiophen-2-yl)-1,4-thiazepan-4-yl]acetic acid hydrochloride (1:1)