喹硫平

• 常用名: 喹硫平
• 英文名: Quetiapine
• CAS号: 111974-69-7
• 分子量: 383.507
• 密度: 1.3±0.1 g/cm3
• 沸点: 556.5±60.0 °C at 760 mmHg
• 分子式: C₂₁H₂₅N₃O₂S
• 熔点: 172 - 174ºC
• 闪点: 290.4±32.9 °C

喹硫平用途

Quetiapine(Ketipinor)是非典型的抗精神病化合物,可作用于精神分裂,狂躁和抑郁症。

喹硫平名称

• 中文名: 喹硫平
• 英文名: quetiapine
• 中文别名: 11-[4-[2-(2-羟基乙氧基)乙基]-1-哌嗪基]二苯并[b,f][1,4]硫氮杂卓

喹硫平生物活性

• 描述: Quetiapine(Ketipinor)是非典型的抗精神病化合物,可作用于精神分裂,狂躁和抑郁症。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 5-HT受体
  信号通路 >> 神经信号通路 >> 5-HT受体
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Sheehan DV, et al. Long-term functioning and sleep quality in patients with major depressive disorder treated with extended-release quetiapine fumarate. Int Clin Psychopharmacol. 2012 Sep;27(5):239-48.

  [2]. Endicott J, et al. Effects of once-daily extended release quetiapine fumarate on patient-reported outcomes in patients with generalized anxiety disorder. Neuropsychiatr Dis Treat. 2012;8:301-311.

  [3]. Lee JG, et al. Safety of quetiapine fumarate extended release in the treatment of Korean patients with acute schizophrenia. Hum Psychopharmacol. 2012 Jul;27(4):403-10. doi: 10.1002/hup.2241.

  [4]. Thase ME, et al. Extended release quetiapine fumarate in major depressive disorder: analysis in patients with anxious depression. Depress Anxiety. 2012 Jul;29(7):574-86. doi: 10.1002/da.21970.

  [5]. Katila H, et al. Randomized, Double-Blind Study of the Efficacy and Tolerability of Extended Release Quetiapine Fumarate (Quetiapine XR) Monotherapy in Elderly Patients With Major Depressive Disorder.Am J Geriatr Psychiatry. 2012 Jun 7.

喹硫平物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 556.5±60.0 °C at 760 mmHg
• 熔点: 172 - 174ºC
• 分子式: C₂₁H₂₅N₃O₂S
• 分子量: 383.507
• 闪点: 290.4±32.9 °C
• 精确质量: 383.166748
• PSA: 73.60000
• LogP: 1.57
• 外观性状: 白色至灰白色结晶粉末
• 蒸汽压: 0.0±1.6 mmHg at 25°C
• 折射率: 1.653
• 储存条件: -20℃

喹硫平安全信息

• 海关编码: 2934999090

喹硫平海关

• 海关编码: 2934999090
• 中文概述: 2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途
• Summary: 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

喹硫平英文别名

• [14C]-Quetiapine
• quetiapina
• 2-{2-4-(dibenzob,f1,4thiazepin-11-yl)piperazin-1-ylethoxy}ethanol
• 11-(4-[2-(2-hydroxyethoxy)ethyl]-1-piperazinyl)-dibenzo[b,f][1,4]thiazepine
• MFCD08064204
• Seroquel
• 2-(2-(4-dibenzo[b,f][1,4]thiazepine-11-yl-1-piperazinyl)ethoxy)ethanol
• UNII-BGL0JSY5SI
• 11-[4-[2-(2-hydroxyethoxy)ethyl]-1-piperazinyl]dibenzo[b,f][1,4]thiazepine
• 2-[2-(4-benzo[b][1,4]benzothiazepin-6-ylpiperazin-1-yl)ethoxy]ethanol
• Ethanol, 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-
• 2-{[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethyl]oxy}ethanol
• ethanol, 2-2-(4-dibenzob,f1,4thiazepin-11-yl-1-piperazinyl)ethoxy-
• Co-Quetiapine
• 2-{2-[4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl]ethoxy}ethanol
• quetiapinum
• 2-{2-[4-(Dibenzo[b,f][1,4]thiazepin-11-yl)-1-piperazinyl]ethoxy}ethanol
• Quetiapine [INN:BAN]
• 2-(2-(4-Dibenzo(b,f)(1,4)thiazepine-11-yl-1-piperazinyl)ethoxy)ethanol