GLPG0492 R对映体

• 常用名: GLPG0492 R对映体
• 英文名: GLPG0492 (R enantiomer)
• CAS号: 1215085-93-0
• 分子量: 389.32800
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₉H₁₄F₃N₃O₃
• 熔点: N/A
• 闪点: N/A

GLPG0492 R对映体用途

GLPG0492 R enantiomer是GLPG0492的R型对映体,GLPG0492是新型选择性SARM

GLPG0492 R对映体名称

• 中文名: GLPG0492 R对映体
• 英文名: (R)-(+)-4-[2,5-dioxo-4-(hydroxymethyl)-3-methyl-4-phenylimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile

GLPG0492 R对映体生物活性

• 描述: GLPG0492 R enantiomer是GLPG0492的R型对映体,GLPG0492是新型选择性SARM
• 相关类别:
  信号通路 >> 其他 >> 雄激素受体
  研究领域 >> 其他
• 参考文献:

  [1]. Nique F, et al. Identification of a 4-(hydroxymethyl)diarylhydantoin as a selective androgen receptor modulator. J Med Chem. 2012 Oct 11;55(19):8236-47.

  [2]. Cozzoli A, et al. GLPG0492, a novel selective androgen receptor modulator, improves muscle performance in the exercised-mdx mouse model of muscular dystrophy. Pharmacol Res. 2013 Jun;72:9-24.

  [3]. Blanqué R, et al. Characterization of GLPG0492, a selective androgen receptor modulator, in a mouse model of hindlimb immobilization. BMC Musculoskelet Disord. 2014 Sep 3;15:291.

GLPG0492 R对映体物理化学性质

• 分子式: C₁₉H₁₄F₃N₃O₃
• 分子量: 389.32800
• 精确质量: 389.09900
• PSA: 84.64000
• LogP: 2.86618
• 储存条件: 2-8℃

GLPG0492 R对映体英文别名

• (R)-4-[2,5-dioxo-4-hydroxymethyl-3-methyl-4-phenylimidazolidin-1-yl]-2-trifluoromethylbenzonitrile
• GLPG0492 (R enantiomer)