丁酸氢化可的松

更新时间：2024-01-02 09:23:18

丁酸氢化可的松结构式	常用名	丁酸氢化可的松	英文名	Hydrocortisone 17-butyrate
	CAS号	13609-67-1	分子量	432.550
	密度	1.2±0.1 g/cm3	沸点	585.6±50.0 °C at 760 mmHg
	分子式	C₂₅H₃₆O₆	熔点	212 °C
	MSDS	中文版美版	闪点	194.0±23.6 °C

丁酸氢化可的松用途

Hydrocortisone 17-butyrate是肾上腺皮质激素类药物。

中文名	丁酸氢化可的松
英文名	cortisol 17-butyrate
中文别名	氢化可的松17-丁酸酯 \| 17-丁酸皮质醇酯 \| 氢化可的松17丁酸杂质 \| 17-丁酸11β,17,21-三羟基孕-4-烯-3,20-二酮 \| 氢化可的松丁酸酯 \| 氢化可的松丁酸酯
英文别名	更多

描述	Hydrocortisone 17-butyrate是肾上腺皮质激素类药物。
相关类别	信号通路 >> G 蛋白偶联受体/G 蛋白 >> 肾上腺素能受体研究领域 >> 炎症/免疫

密度	1.2±0.1 g/cm3
沸点	585.6±50.0 °C at 760 mmHg
熔点	212 °C
分子式	C₂₅H₃₆O₆
分子量	432.550
闪点	194.0±23.6 °C
精确质量	432.251190
PSA	100.90000
LogP	2.81
外观性状	固体;White to Almost white powder to crystal
蒸汽压	0.0±3.7 mmHg at 25°C
折射率	1.565
储存条件	室温
计算化学	1.疏水参数计算参考值（XlogP）:无 2.氢键供体数量:2 3.氢键受体数量:6 4.可旋转化学键数量:6 5.互变异构体数量:15 6.拓扑分子极性表面积:101 7.重原子数量:31 8.表面电荷:0 9.复杂度:817 10.同位素原子数量:0 11.确定原子立构中心数量:7 12.不确定原子立构中心数量:0 13.确定化学键立构中心数量:0 14.不确定化学键立构中心数量:0 15.共价键单元数量:1

丁酸氢化可的松毒性英文版

个人防护装备	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危害码 (欧洲)	Xn
危险品运输编码	NONH for all modes of transport
WGK德国	2
RTECS号	GM9002000
海关编码	2937210000

Hydrocortisone ...

49757-02-0

~79%

丁酸氢化可的松

13609-67-1

文献：Sugai; Okazaki; Akaboshi Synthesis, 1984 , vol. NO. 8, p. 700 - 701

氢化可的松

50-23-7

丁酸氢化可的松

13609-67-1

文献：US4290962 A1, ;

氢化可的松

50-23-7

原丁酸三甲酯

43083-12-1

丁酸氢化可的松

13609-67-1

氢化可的松 21-丁酸盐

6677-99-2

文献：Steroids, , vol. 42, # 1 p. 23 - 36

丁酸氢化可的松上游产品 2
CAS号50-23-7 氢化可的松 CAS号43083-12-1 原丁酸三甲酯
丁酸氢化可的松下游产品 1
CAS号6677-99-2 氢化可的松 21-丁酸盐

海关编码	2937210000

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Synergistic topical application of salt-processed Phellodendron amurense and Sanguisorba officinalis Linne alleviates atopic dermatitis symptoms by reducing levels of immunoglobulin E and pro-inflammatory cytokines in NC/Nga mice.

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Atopic dermatitis is a chronic inflammatory skin disease, and salt-processed Phellodendron amurense (CPE) and Sanguisorba officinalis Linne (SOE) are widely used as anti-inflammatory agents in Asia. T...

Statistical design for formulation optimization of hydrocortisone butyrate-loaded PLGA nanoparticles.

AAPS PharmSciTech 15(3) , 569-87, (2014)

The aim of this investigation was to develop hydrocortisone butyrate (HB)-loaded poly(D,L-lactic-co-glycolic acid) (PLGA) nanoparticles (NP) with ideal encapsulation efficiency (EE), particle size, an...

LOCOID LIPOCREAM

11b,17,21-Trihydroxypregn-4-ene-3,20-dione 17-Butyrate

Pregn-4-ene-3,20-dione, 11,21-dihydroxy-17-(1-oxobutoxy)-, (11β)-

butanoate de (8S,9S,10R,11S,13S,14S,17R)-11-hydroxy-17-(hydroxyacétyl)-10,13-diméthyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tétradécahydro-1H-cyclopenta[a]phénanthrén-17-yle

Hydrocortisone Butyrate

Hydrocortisone butyrate (JP15/USP)

(8S,9S,10R,11S,13S,14S,17R)-11-Hydroxy-17-(hydroxyacetyl)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ylbutanoat

Hydrocortisone 17-butyrate

(11β)-11,21-Dihydroxy-17-(1-oxobutoxy)pregn-4-ene-3,20-dione

cortisol 17-butyrate

MFCD00083364

EINECS 237-093-4

11β,17,21-Trihydroxypregn-4-ene-3,20-dione 17-Butyrate

(11β)-11,21-Dihydroxy-3,20-dioxopregn-4-en-17-yl butyrate

Butanoic acid, (11β)-11,21-dihydroxy-3,20-dioxopregn-4-en-17-yl ester

(8S,9S,10R,11S,13S,14S,17R)-11-hydroxy-17-(hydroxyacetyl)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl butanoate

locoid

(11β)-11,21-dihydroxy-3,20-dioxopregn-4-en-17-yl butanoate

Hydrocortisone butyrate [USAN:BAN:JAN]

Pregn-4-ene-3,20-dione, 11,21-dihydroxy-17-(1-oxobutoxy)-, (11-β)-

[(8S,9S,10R,11S,13S,14S,17R)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] butanoate