(S)-Seco-Duocarmycin SA

• 常用名: (S)-Seco-Duocarmycin SA
• 英文名: (S)-Seco-Duocarmycin SA
• CAS号: 152785-82-5
• 分子量: 513.927
• 密度: 1.5±0.1 g/cm3
• 沸点: 773.9±60.0 °C at 760 mmHg
• 分子式: C₂₅H₂₄ClN₃O₇
• 熔点: N/A
• 闪点: 421.8±32.9 °C

(S)-Seco-Duocarmycin SA用途

(S)-Seco-Duocarmycin SA 是一种 DNA 烷化剂 (DNA alkylator),可作为抗体药物偶联物的毒素部分 (ADC cytotoxin) 起作用。

(S)-Seco-Duocarmycin SA名称

• 英文名: Methyl (8S)-8-(chloromethyl)-4-hydroxy-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]-3,6,7,8-tetrahydropyrrolo[3,2-e]indole-2-carboxylate

(S)-Seco-Duocarmycin SA生物活性

• 描述: (S)-Seco-Duocarmycin SA 是一种 DNA 烷化剂 (DNA alkylator),可作为抗体药物偶联物的毒素部分 (ADC cytotoxin) 起作用。
• 相关类别:
  研究领域 >> 癌症
• 参考文献:

  [1]. Tichenor MS, et al. Systematic exploration of the structural features of yatakemycin impacting DNA alkylation and biological activity. J Am Chem Soc. 2007 Sep 5;129(35):10858-69.

(S)-Seco-Duocarmycin SA物理化学性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 773.9±60.0 °C at 760 mmHg
• 分子式: C₂₅H₂₄ClN₃O₇
• 分子量: 513.927
• 闪点: 421.8±32.9 °C
• 精确质量: 513.130249
• LogP: 1.54
• 蒸汽压: 0.0±2.7 mmHg at 25°C
• 折射率: 1.691

(S)-Seco-Duocarmycin SA英文别名

• Methyl (8S)-8-(chloromethyl)-4-hydroxy-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]-3,6,7,8-tetrahydropyrrolo[3,2-e]indole-2-carboxylate
• Pyrrolo[3,2-e]indole-2-carboxylic acid, 8-(chloromethyl)-3,6,7,8-tetrahydro-4-hydroxy-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]-, methyl ester, (8S)-