PCI-0123

• 常用名: PCI-0123
• 英文名: PCI-0123
• CAS号: 156436-90-7
• 分子量: 1166.12000
• 密度: N/A
• 沸点: 1059.6ºC at 760mmHg
• 分子式: C₅₂H₇₂LuN₅O₁₄++++
• 熔点: N/A
• 闪点: 594.6ºC

PCI-0123用途

Motexafin lutetium is a texaphyrin, marketed as Antrin by Pharmacyclics Inc. Motexafin lutetium is structurally a pentadentate aromatic metallotexaphyrin with photosensitizing properties. Motexafin lutetium preferentially accumulates in tumor cells due to their increased rates of metabolism and absorbs light, forming an extended high energy conformational state that produces high quantum yields of singlet oxygen, resulting in local cytotoxic effects. M otexafin lutetium is a photosensitiser for use in photodynamic therapy to treat skin conditions and superficial cancers. It has also been tested for use in photoangioplasty (photodynamic treatment of diseased arteries). It is photoactivated by 732 nm light which allows greater depth of penetration.

PCI-0123名称

• 英文名: Motexafin Lutetium Hydrate

PCI-0123物理化学性质

• 沸点: 1059.6ºC at 760mmHg
• 分子式: C₅₂H₇₂LuN₅O₁₄++++
• 分子量: 1166.12000
• 闪点: 594.6ºC
• 精确质量: 1165.45000
• PSA: 203.01000
• LogP: 4.59870
• 蒸汽压: 0mmHg at 25°C

PCI-0123英文别名

• Bis(acetato-O)[9,10-diethyl-20,21-bis[2-[2-(2-methoxyethoxy) ethoxy]ethoxy]-4,15-dimethyl-8,11-imino-6,3_13,16-dinitrilo -1,18-benzodiazacycloeicosine-5,14-dipropanolato-N1,N18,N23,N24,N25]Lutetium hydrate