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妊娠二醇3Α单葡萄糖醛酸苷

更新时间:2024-01-04 15:36:42

妊娠二醇3Α单葡萄糖醛酸苷结构式
妊娠二醇3Α单葡萄糖醛酸苷结构式
品牌特惠专场
常用名 妊娠二醇3Α单葡萄糖醛酸苷 英文名 Pregnanediol 3-glucuronide
CAS号 1852-49-9 分子量 496.63300
密度 1.3g/cm3 沸点 666.4ºC at 760mmHg
分子式 C27H44O8 熔点 >94°C (dec.) (lit.)
MSDS 美版 闪点 217.2ºC

 妊娠二醇3Α单葡萄糖醛酸苷用途


孕二醇3-葡萄糖醛酸是孕酮的主要终末代谢产物,在生理过程中发挥重要作用,如女性月经周期、妊娠(支持妊娠)、胚胎发生和人类及其他物种的母体免疫反应[1]。

 妊娠二醇3Α单葡萄糖醛酸苷名称

中文名 3-Alpha,20alpha-二羟基-5beta-孕甾3-葡糖苷酸
英文名 Pregnanediol 3α-O-β-D-Glucuronide
英文别名 更多

 妊娠二醇3Α单葡萄糖醛酸苷生物活性

描述 孕二醇3-葡萄糖醛酸是孕酮的主要终末代谢产物,在生理过程中发挥重要作用,如女性月经周期、妊娠(支持妊娠)、胚胎发生和人类及其他物种的母体免疫反应[1]。
相关类别
靶点

Human Endogenous Metabolite

参考文献

[1]. Chen J, et al. Quantitation of serum pregnanediol-3-glucuronide level in different endocrine statuses by LC-MS/MS. J Pharm Biomed Anal. 2020;184:113171.

 妊娠二醇3Α单葡萄糖醛酸苷物理化学性质

密度 1.3g/cm3
沸点 666.4ºC at 760mmHg
熔点 >94°C (dec.) (lit.)
分子式 C27H44O8
分子量 496.63300
闪点 217.2ºC
精确质量 496.30400
PSA 136.68000
LogP 2.30350
外观性状 白色至浅米色固体
蒸汽压 1.34E-20mmHg at 25°C
折射率 1.587
储存条件 20°C,惰性气体

 妊娠二醇3Α单葡萄糖醛酸苷安全信息

个人防护装备 Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危险品运输编码 NONH for all modes of transport
WGK德国 3

 妊娠二醇3Α单葡萄糖醛酸苷合成线路

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妊娠二醇3Α单葡萄糖醛酸苷结构式

妊娠二醇3Α单葡萄糖醛酸苷

1852-49-9

文献:Huebner et al. Journal of Biological Chemistry, 1944 , vol. 155, p. 615

 妊娠二醇3Α单葡萄糖醛酸苷上下游产品

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 妊娠二醇3Α单葡萄糖醛酸苷文献25

更多文献
Progesterone, pregnanediol-3-glucuronide, relaxin and oestrone sulphate concentrations in saliva, milk and urine of female alpacas (Vicugna pacos) and their application in pregnancy diagnosis.

Vet. Rec. 171(8) , 195, (2012)

The pregnancy-associated hormones, progesterone (P4), pregnanediol-3-glucuronide (PdG), relaxin (RLN) and oestrone sulphate (E1S) in plasma, saliva, milk and urine of alpacas were measured in order to...

Factors related to declining luteal function in women during the menopausal transition.

J. Clin. Endocrinol. Metab. 93(5) , 1711-21, (2008)

Reproductive hormones are incompletely characterized during the menopause transition (MT).Increased anovulation and decreased progesterone accompany progress through the MT.The Daily Hormone Study (DH...

Describing ovarian cycles, pregnancy characteristics, and the use of contraception in female white-faced marmosets, Callithrix geoffroyi.

Am. J. Primatol. 74(11) , 1044-53, (2012)

Endocrine data and characteristics of nonconceptive ovarian cycling and pregnancy are limited within the genus Callithrix to the common marmoset (C. jacchus) and Wied's black tufted-ear marmoset (C. k...

 妊娠二醇3Α单葡萄糖醛酸苷英文别名

3alpha,20alpha-dihydroxy-5beta-pregnane 3-glucuronide