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泰利霉素

更新时间:2024-01-06 12:36:56

泰利霉素结构式
泰利霉素结构式
品牌特惠专场
常用名 泰利霉素 英文名 Telithromycin
CAS号 191114-48-4 分子量 812.004
密度 1.3±0.1 g/cm3 沸点 966.2±65.0 °C at 760 mmHg
分子式 C43H65N5O10 熔点 176-188ºC
MSDS N/A 闪点 538.2±34.3 °C

 泰利霉素用途


Telithromycin(HMR3647)为可作用于社区获得性肺炎的抗生素。

 泰利霉素名称

中文名 泰利霉素
英文名 Telithromycin
中文别名 红霉酮(特利霉素)
英文别名 更多

 泰利霉素生物活性

描述 Telithromycin(HMR3647)为可作用于社区获得性肺炎的抗生素。
相关类别
参考文献

[1]. http://en.wikipedia.org/wiki/Telithromycin

 泰利霉素物理化学性质

密度 1.3±0.1 g/cm3
沸点 966.2±65.0 °C at 760 mmHg
熔点 176-188ºC
分子式 C43H65N5O10
分子量 812.004
闪点 538.2±34.3 °C
精确质量 811.473145
PSA 171.85000
LogP 4.52
蒸汽压 0.0±0.3 mmHg at 25°C
折射率 1.589
储存条件 -20?C Freezer

 泰利霉素安全信息

危害码 (欧洲) Xi
风险声明 (欧洲) R36/37/38
安全声明 (欧洲) 26-36

 泰利霉素合成线路

~99%

泰利霉素结构式

泰利霉素

191114-48-4

文献:ALEMBIC LIMITED Patent: US2008/51352 A1, 2008 ; Location in patent: Page/Page column 14 ;

~99%

泰利霉素结构式

泰利霉素

191114-48-4

文献:ALEMBIC LIMITED Patent: WO2008/23383 A1, 2008 ; Location in patent: Page/Page column 22 ;

~%

泰利霉素结构式

泰利霉素

191114-48-4

文献:WO2005/105821 A2, ; Page/Page column 22 ;

~49%

泰利霉素结构式

泰利霉素

191114-48-4

文献:Denis, Alexis; Agouridas, Constantin; Auger, Jean-Michel; Benedetti, Yannick; Bonnefoy, Alain; Bretin, Francois; Chantot, Jean-Francois; Dussarat, Arlette; Fromentin, Claude; Gouin D'Ambrieres, Solange; Lachaud, Sylvette; Laurin, Patrick; Le Martret, Odile; Loyau, Veronique; Tessot, Nicole; Pejac, Jean-Marie; Perron, Sebastien Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 21 p. 3075 - 3080

~%

泰利霉素结构式

泰利霉素

191114-48-4

文献:Bioorganic and Medicinal Chemistry Letters, , vol. 9, # 21 p. 3075 - 3080

~%

泰利霉素结构式

泰利霉素

191114-48-4

文献:Bioorganic and Medicinal Chemistry Letters, , vol. 9, # 21 p. 3075 - 3080

~%

泰利霉素结构式

泰利霉素

191114-48-4

文献:Journal of Chemical Research, , vol. 37, # 2 p. 107 - 109

~%

泰利霉素结构式

泰利霉素

191114-48-4

文献:Journal of Chemical Research, , vol. 37, # 2 p. 107 - 109

~%

泰利霉素结构式

泰利霉素

191114-48-4

文献:Journal of Chemical Research, , vol. 37, # 2 p. 107 - 109

 泰利霉素英文别名

2H-Oxacyclotetradecino[4,3-d]oxazole-2,6,8,14(1H,7H,9H)-tetrone, 4-ethyloctahydro-11-methoxy-3a,7,9,11,13,15-hexamethyl-1-[4-[4-(3-pyridinyl)-1H-imidazol-1-yl]butyl]-10-[[3,4,6-trideoxy-3-(dimethylami ;no)-β-D-xylo-hexopyranosyl]oxy]-, (3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-
KETEK
(3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-4-ethyl-11-methoxy-3a,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxo-1-[4-(4-pyridin-3-yl-1H-imidazol-1-yl)butyl]tetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranoside
(3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-10-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-4-ethyl-11-methoxy-3a,7,9,11,13,15-hexamethyl-1-[4-(4-pyridin-3-yl-1H-imidazol-1-yl)butyl]octahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-2,6,8,14(1H,7H,9H)-tetron
(3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-4-Ethyl-11-methoxy-3a,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxo-1-{4-[4-(3-pyridinyl)-1H-imidazol-1-yl]butyl}tetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol ;-10-yl 3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranoside
Telithromycin
(3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-4-Ethyl-11-methoxy-3a,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxo-1-{4-[4-(pyridin-3-yl)-1H-imidazol-1-yl]butyl}tetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranoside
(3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-10-{[(2S,3R,4S,6R)-4-(diméthylamino)-3-hydroxy-6-méthyltétrahydro-2H-pyran-2-yl]oxy}-4-éthyl-11-méthoxy-3a,7,9,11,13,15-hexaméthyl-1-[4-(4-pyridin-3-yl-1H-imidazol-1-yl)butyl]octahydro-2H-oxacyclotétradécino[4,3-d][1,3]oxazole-2,6,8,14(1H,7H,9H)-tétrone
(1R,2R,4R,6S,7R,8R,10R,13R,14S)-7-[(2S,3R,4S,6R)-4-Dimethylamino-3-hydroxy-6-methyloxan-2-yl]oxy-13-ethyl-6-methoxy-2,4,6,8,10,14-hexamethyl-17-[4-(4-pyridin-3-ylimidazol-1-yl)butyl]-12,15-dioxa-17-azabicyclo[12.3.0]heptadecane-3,9,11,16-tetrone
(3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-10-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-4-ethyl-11-methoxy-3a,7,9,11,13,15-hexamethyl-1-[4-(4-pyridin-3-yl-1H-imidazol-1-yl)butyl]octahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazole-2,6,8,14(1H,7H,9H)-tetrone
2H-oxacyclotetradecino[4,3-d]oxazole-2,6,8,14(1H,7H,9H)-tetrone, 4-ethyloctahydro-11-methoxy-3a,7,9,11,13,15-hexamethyl-1-[4-[4-(3-pyridinyl)-1H-imidazol-1-yl]butyl]-10-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-
MFCD04117983
3-De((2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy)-11,12-dideoxy-6-O-methyl-3-oxo-12,11-(oxycarbonyl((4-(4-(3-pyridinyl)-1H-imidazol-1-yl)butyl)imino))erythromycin
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