Muscarine chloride

更新时间：2024-01-05 19:13:18

Muscarine chloride结构式	常用名	Muscarine chloride	英文名	(+)-Muscarine (chloride)
	CAS号	2303-35-7	分子量	209.71400
	密度	N/A	沸点	N/A
	分子式	C₉H₂₀ClNO₂	熔点	N/A
	MSDS	中文版美版	闪点	N/A
	符号	GHS06	信号词	Danger

Muscarine chloride用途

毒蕈碱(+)-氯化毒蕈碱是一种能刺激副交感神经系统的毒素。毒蕈碱是一种原型毒蕈碱乙酰胆碱受体激动剂[1][2]。

英文名	(+)-muscarine chloride
英文别名	更多

描述	毒蕈碱(+)-氯化毒蕈碱是一种能刺激副交感神经系统的毒素。毒蕈碱是一种原型毒蕈碱乙酰胆碱受体激动剂[1][2]。
相关类别	信号通路 >> 神经信号通路 >> mAChR 信号通路 >> G 蛋白偶联受体/G 蛋白 >> 由mAChR 研究领域 >> 神经疾病
体外研究	毒蕈碱给药(100 µM)诱导细胞内钙信号振幅,类似于10 µM ACh[1]。毒蕈碱(1-30μM)在NRM神经元上含有5-羟色胺(5-HT)的NRM细胞亚群中产生剂量依赖性超极化[2]。
参考文献	[1]. Beatrice Mihaela Radu, et al. All muscarinic acetylcholine receptors (M 1-M 5) are expressed in murine brain microvascular endothelium. Sci Rep. 2017 Jul 11;7(1):5083. [2]. Z Z Pan, et al. Muscarine hyperpolarizes a subpopulation of neurons by activating an M2 muscarinic receptor in rat nucleus raphe magnus in vitro. J Neurosci. 1994 Mar;14(3 Pt 1):1332-8.

分子式	C₉H₂₀ClNO₂
分子量	209.71400
精确质量	209.11800
PSA	29.46000
LogP	1.03290
储存条件	-20°C，密闭，干燥

符号	GHS06
信号词	Danger
危害声明	H300-H310-H330
警示性声明	P260-P264-P280-P284-P302 + P350-P310
个人防护装备	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
危险品运输编码	UN 2811 6.1 / PGII
RTECS号	QG3500000

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