Hyperforin dicyclohexylammonium salt

更新时间：2024-01-07 07:44:35

Hyperforin dicyclohexylammonium salt结构式	常用名	Hyperforin dicyclohexylammonium salt	英文名	Hyperforin dicyclohexylammonium salt
	CAS号	238074-03-8	分子量	718.10300
	密度	N/A	沸点	N/A
	分子式	C₄₇H₇₅NO₄	熔点	N/A
	MSDS	中文版美版	闪点	N/A
	符号	GHS05, GHS07, GHS09	信号词	Danger

Hyperforin dicyclohexylammonium salt用途

Hyperforin dicyclohexylammonium salt (Hyperforin DCHA) 是一种瞬时受体典型 6 (TRPC6) 通道激活剂。Hyperforin dicyclohexylammonium salt 通过激活 Ca2+ 传导非选择性典型 TRPC6 通道来调节 Ca2+ 水平。Hyperforin dicyclohexylammonium salt 具有抗抑郁作用。

英文名	N-cyclohexylcyclohexanamine,(1R,5R,6R,7S)-2-hydroxy-6-methyl-1,3,7-tris(3-methylbut-2-enyl)-6-(4-methylpent-3-enyl)-5-(2-methylpropanoyl)bicyclo[3.3.1]non-2-ene-4,9-dione
英文别名	更多

描述	Hyperforin dicyclohexylammonium salt (Hyperforin DCHA) 是一种瞬时受体典型 6 (TRPC6) 通道激活剂。Hyperforin dicyclohexylammonium salt 通过激活 Ca2+ 传导非选择性典型 TRPC6 通道来调节 Ca2+ 水平。Hyperforin dicyclohexylammonium salt 具有抗抑郁作用。
相关类别	信号通路 >> 跨膜转运 >> 钙通道信号通路 >> 跨膜转运 >> TRP频道研究领域 >> 神经疾病
体外研究	高福林二环己基铵盐(Hyperforin-DCHA)具有多向作用机制。它阻断配体门控(GABA、NMDA和AMPA受体)和电压门控通道(Ca2+、K+和Na+)[2]的电导。
参考文献	[1]. Heiser JH, et al. TRPC6 channel-mediated neurite outgrowth in PC12 cells and hippocampal neurons involves activation of RAS/MEK/ERK, PI3K, and CAMKIV signaling. J Neurochem. 2013 Nov;127(3):303-13. [2]. Pochwat B, et al. Hyperforin Potentiates Antidepressant-Like Activity of Lanicemine in Mice. Front Mol Neurosci. 2018 Dec 12;11:456.

分子式	C₄₇H₇₅NO₄
分子量	718.10300
精确质量	717.57000
PSA	83.47000
LogP	12.62200
储存条件	-20°C，密闭，干燥

符号	GHS05, GHS07, GHS09
信号词	Danger
危害声明	H302-H314-H400
警示性声明	P273-P280-P305 + P351 + P338-P310
危险品运输编码	UN 1759 8 / PGIII

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hyperforin dicyclohexylammonium salt

Hyp-DCHA Hyperforin-DCHA

Hyp-DCHA

Hyperforin-DCHA