(D-Trp8,D-Cys14)-Somatostatin-14

• 常用名: (D-Trp8,D-Cys14)-Somatostatin-14
• 英文名: (D-Trp8,D-Cys14)-Somatostatin-14
• CAS号: 61950-59-2
• 分子量: 1536.774
• 密度: 1.5±0.1 g/cm3
• 沸点: N/A
• 分子式: C₇₆H₁₀₄N₁₈O₁₉S₂
• 熔点: N/A
• 闪点: N/A

(D-Trp8,D-Cys14)-Somatostatin-14用途

(D-Trp8,D-Cys14)-生长抑素-14是生长抑素的合成类似物。(D-Trp8,D-Cys14)-生长抑素-14可用于代谢相关疾病的研究[1][2]。

(D-Trp8,D-Cys14)-Somatostatin-14名称

• 英文名: (d-trp8,d-cys14)-somatostatin-14

(D-Trp8,D-Cys14)-Somatostatin-14生物活性

• 描述: (D-Trp8,D-Cys14)-生长抑素-14是生长抑素的合成类似物。(D-Trp8,D-Cys14)-生长抑素-14可用于代谢相关疾病的研究[1][2]。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 代谢疾病
• 体内研究: (D-Trp8,D-Cys14)-生长抑素-14(12μg/100g；i.p.)不改变仓鼠肠道碳水化合物的体内吸收,但抑制雌性动物刷状缘乳糖酶活性[2]。
• 参考文献:

  [1]. Vécsei L, et, al. Somatostatin and (D-Trp8, D-Cys14)-somatostatin delay extinction and reverse electroconvulsive shock induced amnesia in rats. Psychoneuroendocrinology. 1986;11(1):111-5.

  [2]. Martínez-Sapiña J, et, al. Somatostatin and its analogue (D-Trp8,D-Cys14)-somatostatin do not modify intestinal absorption in vivo of carbohydrates in hamster intestine, but they do modify some disaccharidases. Q J Exp Physiol. 1989 Nov;74(6):851-6.

(D-Trp8,D-Cys14)-Somatostatin-14物理化学性质

• 密度: 1.5±0.1 g/cm3
• 分子式: C₇₆H₁₀₄N₁₈O₁₉S₂
• 分子量: 1536.774
• 精确质量: 1535.668945
• PSA: 663.83000
• LogP: -6.45
• 折射率: 1.681

(D-Trp8,D-Cys14)-Somatostatin-14英文别名

• 1,2-Dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriaconta-5,8,11,17,20,23,26,29,32,35-decaene-4-carboxylic acid, 19,34-bis(4-aminobutyl)-6,9,12,18,21,24,27,30,33,36-decahydroxy-10-[(1R)-1-hydroxyethyl]-31-(2-hydroxy-2-iminoethyl)-7-(hydroxymethyl)-37-[[1-hydroxy-2-(methylamino)ethylidene]amino]-22-(1H-indol-3-ylmethyl)-15-oxo-13,25,28-tris(phenylmethyl)-, (4S,7S,8E,10S,13S,17E,19S,22R,25S,28S,31S,34S,35E,37R)-
• (4S,7S,8E,10S,13S,17E,19S,22R,25S,28S,31S,34S,35E,37R)-19,34-Bis(4-aminobutyl)-13,25,28-tribenzyl-6,9,12,18,21,24,27,30,33,36-decahydroxy-10-[(1R)-1-hydroxyethyl]-31-(2-hydroxy-2-iminoethyl)-7-(hydroxymethyl)-37-{[1-hydroxy-2-(methylamino)ethylidene]amino}-22-(1H-indol-3-ylmethyl)-15-oxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriaconta-5,8,11,17,20,23,26,29,32,35-decaene-4-carboxylic acid