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21-脱氧皮质醇

更新时间:2024-01-04 16:30:32

21-脱氧皮质醇结构式
21-脱氧皮质醇结构式
品牌特惠专场
常用名 21-脱氧皮质醇 英文名 11beta,17alpha-dihydroxy-4-pregnene-3,20-dione
CAS号 641-77-0 分子量 346.46100
密度 1.21g/cm3 沸点 523.9ºC at 760 mmHg
分子式 C21H30O4 熔点 N/A
MSDS 中文版 美版 闪点 284.7ºC
符号 GHS02 GHS06 GHS08
GHS02, GHS06, GHS08
信号词 Danger

 21-脱氧皮质醇用途


21脱氧皮质醇是一种内源性代谢产物。21脱氧皮质素是先天性肾上腺增生的标志[1]。

 21-脱氧皮质醇名称

中文名 11beta,17alpha-二羟基-4-孕烯-3,20-二酮
英文名 11beta,17alpha-dihydroxy-4-pregnene-3,20-dione
英文别名 更多

 21-脱氧皮质醇生物活性

描述 21脱氧皮质醇是一种内源性代谢产物。21脱氧皮质素是先天性肾上腺增生的标志[1]。
相关类别
靶点

Human Endogenous Metabolite

参考文献

[1]. Franks RC. Plasma 17-hydroxyprogesterone, 21-deoxycortisol and cortisol in congenital adrenal hyperplasia. J Clin Endocrinol Metab. 1974;39(6):1099-1102.

 21-脱氧皮质醇物理化学性质

密度 1.21g/cm3
沸点 523.9ºC at 760 mmHg
分子式 C21H30O4
分子量 346.46100
闪点 284.7ºC
精确质量 346.21400
PSA 74.60000
LogP 2.80920
折射率 1.576
储存条件 ?20°C

 21-脱氧皮质醇安全信息

符号 GHS02 GHS06 GHS08
GHS02, GHS06, GHS08
信号词 Danger
危害声明 H225-H301 + H311 + H331-H370
警示性声明 P210-P260-P280-P301 + P310-P311
个人防护装备 Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危害码 (欧洲) F,T
风险声明 (欧洲) 11-23/24/25-39/23/24/25
安全声明 (欧洲) 7-16-36/37-45
危险品运输编码 UN1230 - class 3 - PG 2 - Methanol, solution

 21-脱氧皮质醇合成线路

 21-脱氧皮质醇文献28

更多文献
An LC-MS/MS method for steroid profiling during adrenal venous sampling for investigation of primary aldosteronism.

J. Steroid Biochem. Mol. Biol. 145 , 75-84, (2015)

Steroid profiling for diagnosis of endocrine disorders featuring disordered production of steroid hormones is now possible from advances in liquid chromatography with tandem mass spectrometry (LC-MS/M...

Hirsutism and acne in women: coordinated radioimmunoassays for eight relevant plasma steroids.

Clin. Chem. 40(12) , 2296-305, (1994)

We developed and validated a coordinated set of RIAs for the following eight steroids in single small aliquots (< or = 1 mL) of plasma: androstenedione, dehydroepiandrosterone, 11-deoxycortisol, 21-de...

Superior discriminating value of ACTH-stimulated serum 21-deoxycortisol in identifying heterozygote carriers for 21-hydroxylase deficiency.

Clin. Endocrinol. (Oxf.) 73(6) , 700-6, (2010)

Congenital adrenal hyperplasia caused by classic 21-hydroxylase deficiency (21OHD) is an autosomal recessive disorder with a high prevalence of asymptomatic heterozygote carriers (HTZ) in the general ...

 21-脱氧皮质醇英文别名

21-deoxycortisol
21-Deoxyhydrocortisone
21-Dehydrohydrocortisone
21-DESOXYCORTISOL
21 DEOXYCORTISOL 21-DESOXYCORTISOL
4-pregnene-11-B-17-A-diol-3-20-dione
4-Pregnen-11,17a-diol-3,20-dione-d8
EINECS 211-375-7
品牌现货直购
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