鲑鱼促黄体激素释放激素结构式
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常用名 | 鲑鱼促黄体激素释放激素 | 英文名 | LHRH (salmon) acetate salt |
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CAS号 | 86073-88-3 | 分子量 | 1212.31000 | |
密度 | N/A | 沸点 | N/A | |
分子式 | C60H73N15O13 | 熔点 | N/A | |
MSDS | 中文版 美版 | 闪点 | N/A | |
符号 |
GHS08 |
信号词 | Danger |
鲑鱼促黄体激素释放激素用途Luteinizing Hormone Releasing Hormone (LH-RH), salmon 是在下丘脑中合成的垂体前体十肽,在控制生殖功能中起关键作用。 |
中文名 | GLP-HIS-TRP-SER-TYR-GLY-LEU-ARG-PRO-GLY-NH2 |
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英文名 | Luteinizing hormone releasing hormone salmon |
英文别名 | 更多 |
描述 | Luteinizing Hormone Releasing Hormone (LH-RH), salmon 是在下丘脑中合成的垂体前体十肽,在控制生殖功能中起关键作用。 |
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相关类别 | |
体外研究 | 促黄体激素释放激素(LHRH)是控制生殖功能的关键激素.LHRH通过激活Gi-cAMP细胞内信号通路起到抗凋亡因子的作用。 LHRH可能作为黑素瘤细胞中细胞增殖和转移行为的抑制因子[1]。下丘脑十肽促黄体激素释放激素(LHRH)通过刺激垂体促黄体激素(LH)和促卵泡激素(FSH)的释放在控制生殖中发挥核心作用,从而促进性腺功能和调节性类固醇。分泌。 LHRH的作用是由高亲和力G蛋白偶联的LHRH受体(LHRH-R)介导垂体促性腺激素。对LHRH的反应在不同条件下有所不同,并且关键取决于给予给予促性腺细胞的给药方案和剂量[2]。 |
参考文献 |
分子式 | C60H73N15O13 |
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分子量 | 1212.31000 |
精确质量 | 1211.55000 |
PSA | 426.02000 |
LogP | 2.37720 |
储存条件 | -20°C |
符号 |
GHS08 |
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信号词 | Danger |
危害声明 | H360 |
警示性声明 | P201-P308 + P313 |
个人防护装备 | Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
危害码 (欧洲) | T: Toxic; |
风险声明 (欧洲) | R60 |
安全声明 (欧洲) | 53-22-36/37/39-45 |
危险品运输编码 | NONH for all modes of transport |
WGK德国 | 3.0 |
Direct regulation of gonadotrophin-releasing hormone (GnRH) transcription by RF-amide-related peptide-3 and kisspeptin in a novel GnRH-secreting cell line, mHypoA-GnRH/GFP.
J. Neuroendocrinol. 26(12) , 888-97, (2014) RF-amide-related peptide-3 [RFRP-3; also often referred to as the mammalian orthologue of the avian gonadotrophin-inhibitory hormone (GnIH)] and kisspeptin have emerged as potent modulators of neuroen... |
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Histidine(7.36(305)) in the conserved peptide receptor activation domain of the gonadotropin releasing hormone receptor couples peptide binding and receptor activation.
Mol. Cell. Endocrinol. 402 , 95-106, (2015) Transmembrane helix seven residues of G protein-coupled receptors (GPCRs) couple agonist binding to a conserved receptor activation mechanism. Amino-terminal residues of the GnRH peptide determine ago... |
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Live birth rates after combined adjuvant therapy in IVF-ICSI cycles: a matched case-control study.
Reprod. Biomed. Online 30(4) , 340-8, (2015) The effectiveness of combined co-treatment with aspirin, doxycycline, prednisolone, with or without oestradiol patches, was investigated on live birth (LBR) rates after fresh and frozen embryo transfe... |
pyr-his-trp-ser-tyr-gly-trp-leu-pro-gly-nh2 |
Pyr-HWSYGWLPG-NH2 |
Luteinizing Hormone Releasing Hormone (LH-RH), salmon |