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鲑鱼促黄体激素释放激素

更新时间:2024-01-02 16:33:58

鲑鱼促黄体激素释放激素结构式
鲑鱼促黄体激素释放激素结构式
品牌特惠专场
常用名 鲑鱼促黄体激素释放激素 英文名 LHRH (salmon) acetate salt
CAS号 86073-88-3 分子量 1212.31000
密度 N/A 沸点 N/A
分子式 C60H73N15O13 熔点 N/A
MSDS 中文版 美版 闪点 N/A
符号 GHS08
GHS08
信号词 Danger

 鲑鱼促黄体激素释放激素用途


Luteinizing Hormone Releasing Hormone (LH-RH), salmon 是在下丘脑中合成的垂体前体十肽,在控制生殖功能中起关键作用。

 鲑鱼促黄体激素释放激素名称

中文名 GLP-HIS-TRP-SER-TYR-GLY-LEU-ARG-PRO-GLY-NH2
英文名 Luteinizing hormone releasing hormone salmon
英文别名 更多

 鲑鱼促黄体激素释放激素生物活性

描述 Luteinizing Hormone Releasing Hormone (LH-RH), salmon 是在下丘脑中合成的垂体前体十肽,在控制生殖功能中起关键作用。
相关类别
体外研究 促黄体激素释放激素(LHRH)是控制生殖功能的关键激素.LHRH通过激活Gi-cAMP细胞内信号通路起到抗凋亡因子的作用。 LHRH可能作为黑素瘤细胞中细胞增殖和转移行为的抑制因子[1]。下丘脑十肽促黄体激素释放激素(LHRH)通过刺激垂体促黄体激素(LH)和促卵泡激素(FSH)的释放在控制生殖中发挥核心作用,从而促进性腺功能和调节性类固醇。分泌。 LHRH的作用是由高亲和力G蛋白偶联的LHRH受体(LHRH-R)介导垂体促性腺激素。对LHRH的反应在不同条件下有所不同,并且关键取决于给予给予促性腺细胞的给药方案和剂量[2]。
参考文献

[1]. Moretti RM, et al. Inhibitory activity of luteinizing hormone-releasing hormone on tumor growth and progression. Endocr Relat Cancer. 2003 Jun;10(2):161-7.

[2]. Horvath JE, et al. Effects of long-term treatment with the luteinizing hormone-releasing hormone (LHRH) agonist Decapeptyl and the LHRH antagonist Cetrorelix on the levels of pituitary LHRH receptors and their mRNA expression in rats. Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):15048-53.

 鲑鱼促黄体激素释放激素物理化学性质

分子式 C60H73N15O13
分子量 1212.31000
精确质量 1211.55000
PSA 426.02000
LogP 2.37720
储存条件 -20°C

 鲑鱼促黄体激素释放激素安全信息

符号 GHS08
GHS08
信号词 Danger
危害声明 H360
警示性声明 P201-P308 + P313
个人防护装备 Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
危害码 (欧洲) T: Toxic;
风险声明 (欧洲) R60
安全声明 (欧洲) 53-22-36/37/39-45
危险品运输编码 NONH for all modes of transport
WGK德国 3.0

 鲑鱼促黄体激素释放激素文献188

更多文献
Direct regulation of gonadotrophin-releasing hormone (GnRH) transcription by RF-amide-related peptide-3 and kisspeptin in a novel GnRH-secreting cell line, mHypoA-GnRH/GFP.

J. Neuroendocrinol. 26(12) , 888-97, (2014)

RF-amide-related peptide-3 [RFRP-3; also often referred to as the mammalian orthologue of the avian gonadotrophin-inhibitory hormone (GnIH)] and kisspeptin have emerged as potent modulators of neuroen...

Histidine(7.36(305)) in the conserved peptide receptor activation domain of the gonadotropin releasing hormone receptor couples peptide binding and receptor activation.

Mol. Cell. Endocrinol. 402 , 95-106, (2015)

Transmembrane helix seven residues of G protein-coupled receptors (GPCRs) couple agonist binding to a conserved receptor activation mechanism. Amino-terminal residues of the GnRH peptide determine ago...

Live birth rates after combined adjuvant therapy in IVF-ICSI cycles: a matched case-control study.

Reprod. Biomed. Online 30(4) , 340-8, (2015)

The effectiveness of combined co-treatment with aspirin, doxycycline, prednisolone, with or without oestradiol patches, was investigated on live birth (LBR) rates after fresh and frozen embryo transfe...

 鲑鱼促黄体激素释放激素英文别名

pyr-his-trp-ser-tyr-gly-trp-leu-pro-gly-nh2
Pyr-HWSYGWLPG-NH2
Luteinizing Hormone Releasing Hormone (LH-RH), salmon
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