Ibudilast-d3
Modify Date: 2024-01-05 12:14:37
Ibudilast-d3 structure
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Common Name | Ibudilast-d3 | ||
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| CAS Number | 102064-45-9 | Molecular Weight | 230.30600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H18N2O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Ibudilast-d3Ibudilast-d3 (KC-404-d3) is the deuterium labeled Ibudilast. Ibudilast (KC-404) is a cyclic AMP phosphodiesterase (PDE) inhibitor. Ibudilast has platelet anti-aggregatory effects. Ibudilast can be used for the research of asthma for its inhibitory effects on tracheal smooth muscle contractility. Ibudilast may be a useful neuroprotective and anti-dementia agent counteracting neurotoxicity in activated microglia[1][2]. |
| Name | 2-methyl-1-(4,5,6,7-tetradeuterio-2-propan-2-ylpyrazolo[1,5-a]pyridin-3-yl)propan-1-one |
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| Synonym | More Synonyms |
| Description | Ibudilast-d3 (KC-404-d3) is the deuterium labeled Ibudilast. Ibudilast (KC-404) is a cyclic AMP phosphodiesterase (PDE) inhibitor. Ibudilast has platelet anti-aggregatory effects. Ibudilast can be used for the research of asthma for its inhibitory effects on tracheal smooth muscle contractility. Ibudilast may be a useful neuroprotective and anti-dementia agent counteracting neurotoxicity in activated microglia[1][2]. |
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| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
| Molecular Formula | C14H18N2O |
|---|---|
| Molecular Weight | 230.30600 |
| Exact Mass | 230.14200 |
| PSA | 34.37000 |
| LogP | 3.29640 |
| Hazard Codes | Xi |
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| 3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine-d3 |
| AV 411-d3 |
| 1-(2-Isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-methylpropan-1-one-d3 |
| Ketas-d3 |
| Ibudilast-d3 (Major) |
| KC 404-d3 |
| 2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]-1-propanone-d3 |
| 2-Isopropyl-3-isobutyrylpyrazolo[1,5-a]pyridine-d3 |