B 746
Modify Date: 2024-01-13 09:43:15
B 746 structure
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Common Name | B 746 | ||
|---|---|---|---|---|
| CAS Number | 103051-26-9 | Molecular Weight | 459.37 | |
| Density | 1.3g/cm3 | Boiling Point | 561.5ºC at 760mmHg | |
| Molecular Formula | C26H20Cl2N4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 293.4ºC | |
Use of B 746B746 is a clofazimine analog with anti-Mycobacterium avium complex (MAC) activity and is less effective when used with clofazimine or streptomycin[1]. |
| Name | N,5-bis(4-chlorophenyl)-3-ethyliminophenazin-2-amine |
|---|---|
| Synonym | More Synonyms |
| Description | B746 is a clofazimine analog with anti-Mycobacterium avium complex (MAC) activity and is less effective when used with clofazimine or streptomycin[1]. |
|---|---|
| Related Catalog | |
| In Vitro | B746（1、3、10 μM；7 天）显著抑制分枝杆菌的生长[1]。 |
| In Vivo | B746 （口服；10、20、30 mg/kg；单剂量；第一天和第 2、4 和 6 周）抑制米色小鼠脾脏中的分枝杆菌生长[1]。 Animal Model: beige mice Dosage: 10, 20, 30 mg/kg Administration: p.o.; 10, 20, 30 mg/kg; single dose; first day and 2, 4 and 6 week after infection Result: Reduced Colony Forming Units (CFU) counts of Mycobacteria in spleen of beige mice. |
| References |
| Density | 1.3g/cm3 |
|---|---|
| Boiling Point | 561.5ºC at 760mmHg |
| Molecular Formula | C26H20Cl2N4 |
| Molecular Weight | 459.37 |
| Flash Point | 293.4ºC |
| Exact Mass | 458.10700 |
| PSA | 42.21000 |
| LogP | 7.22270 |
| Vapour Pressure | 1.24E-12mmHg at 25°C |
| Index of Refraction | 1.674 |
| 3-Aethylamino-2-(4-chlor-anilino)-5-(4-chlor-phenyl)-phenazinium-betain |
| CF Deriv B746 |
| 3-p-Chloroanilino-10-(p-chlorophenyl)-2-(ethylimino)-2,10-dihydrophenazine |
| B 746 |
| 3-ethylamino-2-(4-chloro-anilino)-5-(4-chloro-phenyl)-phenazinium-betaine |