Dalbavancin-d6

Modify Date: 2024-04-09 06:34:23

Dalbavancin-d6 structure	Common Name	Dalbavancin-d6
	CAS Number	1126461-54-8	Molecular Weight	1822.73
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₈₈H₉₄D₆Cl₂N₁₀O₂₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Dalbavancin-d6

Dalbavancin-d6 is the deuterium labeled Dalbavancin[1]. Dalbavancin (MDL-63397) is a semisynthetic lipoglycopeptide antibiotic with potent bactericidal activity against Gram-positive bacteria. Dalbavancin inhibits Staphylococcus aureus and Bacillus anthracis with MIC90s of 0.06 μg/mL and 0.25 μg/mL, respectively[2][3].

Name	Dalbavancin-d6

Description	Dalbavancin-d6 is the deuterium labeled Dalbavancin[1]. Dalbavancin (MDL-63397) is a semisynthetic lipoglycopeptide antibiotic with potent bactericidal activity against Gram-positive bacteria. Dalbavancin inhibits Staphylococcus aureus and Bacillus anthracis with MIC90s of 0.06 μg/mL and 0.25 μg/mL, respectively[2][3].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Heine HS, et al. Activity of dalbavancin against Bacillus anthracis in vitro and in a mouse inhalation anthrax model. Antimicrob Agents Chemother. 2010 Mar;54(3):991-6. [3]. Bennett JW, et al. Dalbavancin in the treatment of complicated skin and soft-tissue infections: a review. Ther Clin Risk Manag. 2008 Feb4(1):31-40.

Molecular Formula	C₈₈H₉₄D₆Cl₂N₁₀O₂₈
Molecular Weight	1822.73

Dalbavancin-d6

Use of Dalbavancin-d6

Names

Dalbavancin-d6 Biological Activity

Chemical & Physical Properties