203645-59-4

203645-59-4 structure

Name: Fenitrothion-d6
Chemical Name: Fenitrothion-d6
CAS Number: 203645-59-4
Molecular Formula: C₉H₆D₆NO₅PS
Molecular Weight: 283.271
Catalog: Signaling Pathways Neuronal Signaling AChE
Create Date: 2018-10-01 12:44:15
Modify Date: 2024-01-12 16:08:34
Fenitrothion-d6 is the deuterium labeled Fenitrothion[1]. Fenitrothion, one of the most widely used organophosphorus pesticides, is a cholinesterase inhibiting insecticide/acaricid. Fenitrothion is widely used, as a broad-spectrum insecticide, on cotton crops, vegetables crops, fruit crops, and field crops especially paddy. Fenitrothion leads to accumulation of nitrophenols[2][3].

Name	Fenitrothion-d6
Synonyms	O,O-Bis[(H)methyl] O-(3-methyl-4-nitrophenyl) phosphorothioate (3-methyl-4-nitrophenoxy)-sulfanylidene-bis(trideuteriomethoxy)-λ<sup>5</sup>-phosphane Phosphorothioic acid, O,O-dimethyl-d O-(3-methyl-4-nitrophenyl) ester

Description	Fenitrothion-d6 is the deuterium labeled Fenitrothion[1]. Fenitrothion, one of the most widely used organophosphorus pesticides, is a cholinesterase inhibiting insecticide/acaricid. Fenitrothion is widely used, as a broad-spectrum insecticide, on cotton crops, vegetables crops, fruit crops, and field crops especially paddy. Fenitrothion leads to accumulation of nitrophenols[2][3].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Neuronal Signaling >> AChE
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Abdel-Ghany R, et al. Impact of Exposure to Fenitrothion on Vital Organs in Rats. J Toxicol. 2016;2016:5609734. [3]. Qing Hong, et al. A microcosm study on bioremediation of fenitrothion-contaminated soil using Burkholderia sp. FDS-1. International Biodeterioration & Biodegradation