3’-Deoxy-3’-fluoro-5-fluorouridine

Modify Date: 2024-03-16 14:08:22

3’-Deoxy-3’-fluoro-5-fluorouridine Structure
3’-Deoxy-3’-fluoro-5-fluorouridine structure
Common Name 3’-Deoxy-3’-fluoro-5-fluorouridine
CAS Number 112668-56-1 Molecular Weight 264.18
Density 1.7±0.1 g/cm3 Boiling Point N/A
Molecular Formula C9H10F2N2O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3’-Deoxy-3’-fluoro-5-fluorouridine


3’-Deoxy-3’-fluoro-5-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 3'-Deoxy-3',5-difluorouridine
Synonym More Synonyms

 3’-Deoxy-3’-fluoro-5-fluorouridine Biological Activity

Description 3’-Deoxy-3’-fluoro-5-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Molecular Formula C9H10F2N2O5
Molecular Weight 264.18
Exact Mass 264.055786
LogP -0.88
Index of Refraction 1.583

 Synonyms

3'-Deoxy-3',5-difluorouridine
Uridine, 3'-deoxy-3',5-difluoro-
MFCD28975240