9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(furan-2-yl)purine

Modify Date: 2024-07-18 21:51:51

9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(furan-2-yl)purine Structure
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(furan-2-yl)purine structure
Common Name 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(furan-2-yl)purine
CAS Number 1612191-89-5 Molecular Weight 318.28
Density 1.8±0.1 g/cm3 Boiling Point 616.6±65.0 °C at 760 mmHg
Molecular Formula C14H14N4O5 Melting Point N/A
MSDS N/A Flash Point 326.7±34.3 °C

 Use of 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(furan-2-yl)purine


9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(furan-2-yl)purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(2-furyl)-9H-purine
Synonym More Synonyms

  Biological Activity

Description 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(furan-2-yl)purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.8±0.1 g/cm3
Boiling Point 616.6±65.0 °C at 760 mmHg
Molecular Formula C14H14N4O5
Molecular Weight 318.28
Flash Point 326.7±34.3 °C
Exact Mass 320.092072
LogP 0.81
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.768

 Synonyms

9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(2-furyl)-9H-purine
9H-Purine, 9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-6-(2-furanyl)-