Ramiprilat-d5

Modify Date: 2024-01-10 18:42:01

Ramiprilat-d5 structure	Common Name	Ramiprilat-d5
	CAS Number	2021255-43-4	Molecular Weight	393.49
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₃D₅N₂O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Ramiprilat-d5

Ramiprilat-d5 is deuterium labeled Ramiprilat. Ramiprilat (HOE 498 diacid), an active metabolite of Ramipril, is a potent and orally active angiotensin converting enzyme (ACE) inhibitor with a Ki value of 7 pM. Ramiprilat can be used for high blood pressure and heart failure research[1].

Name	Ramiprilat-d5

Description	Ramiprilat-d5 is deuterium labeled Ramiprilat. Ramiprilat (HOE 498 diacid), an active metabolite of Ramipril, is a potent and orally active angiotensin converting enzyme (ACE) inhibitor with a Ki value of 7 pM. Ramiprilat can be used for high blood pressure and heart failure research[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Metabolic Enzyme/Protease >> Angiotensin-converting Enzyme (ACE)
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Ramiprilat (HOE 498 diacid), an active metabolite of Ramipril, is a potent and orally active angiotensin converting enzyme (ACE) inhibitor with a Ki value of 7 pM. Ramiprilat can be used for high blood pressure and heart failure research^[1].

Molecular Formula	C₂₁H₂₃D₅N₂O₅
Molecular Weight	393.49

Ramiprilat-d5

Use of Ramiprilat-d5

Names

Ramiprilat-d5 Biological Activity

Chemical & Physical Properties