87269-97-4

87269-97-4 structure

Name: Ramiprilat
Chemical Name: Ramiprilat
CAS Number: 87269-97-4
Molecular Formula: C₂₁H₂₈N₂O₅
Molecular Weight: 388.457
Catalog: API Circulatory system medication Antihypertensive drug
Create Date: 2018-09-24 02:07:23
Modify Date: 2024-01-04 18:31:54
Ramiprilat (HOE 498 diacid), an active metabolite of Ramipril, is a potent and orally active angiotensin converting enzyme (ACE) inhibitor with a Ki value of 7 pM. Ramiprilat can be used for high blood pressure and heart failure research[1].

Name	Ramiprilat
Synonyms	Ramiprilate [French] Ramiprilate (2S,3aS,6aS)-1-[(2S)-2-{[(1S)-1-Carboxy-3-phenylpropyl]amino}propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid 2-[N-((S)-1-carboxy-3-phenylpropyl)-L-alanyl]-(1S,3S,5S)-2-azabicyclo[3.3.0]octane-3-carboxylic acid (2S,3aS,6aS)-1-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acid (2S,3aS,6aS)-1-((S)-N-((S)-1-Carboxy-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid Ramiprilatum Ramiprilat [INN] UNII-6N5U4QFC3G Ramiprilat Ramiprilatum [Latin]

Description	Ramiprilat (HOE 498 diacid), an active metabolite of Ramipril, is a potent and orally active angiotensin converting enzyme (ACE) inhibitor with a Ki value of 7 pM. Ramiprilat can be used for high blood pressure and heart failure research[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Metabolic Enzyme/Protease >> Angiotensin-converting Enzyme (ACE)
Target	Human Endogenous Metabolite
References	[1]. Ramiprilat (HOE 498 diacid), an active metabolite of Ramipril, is a potent and orally active angiotensin converting enzyme (ACE) inhibitor with a Ki value of 7 pM. Ramiprilat can be used for high blood pressure and heart failure research^[1].

Density	1.3±0.1 g/cm3
Boiling Point	632.2±55.0 °C at 760 mmHg
Melting Point	139-141ºC
Molecular Formula	C₂₁H₂₈N₂O₅
Molecular Weight	388.457
Flash Point	336.2±31.5 °C
Exact Mass	388.199829
PSA	106.94000
LogP	2.53
Vapour Pressure	0.0±2.0 mmHg at 25°C
Index of Refraction	1.583
Storage condition	Refrigerator, Under Inert Atmosphere

87333-19-5

87269-97-4

Literature: Arzneimittel-Forschung/Drug Research, , vol. 40, # 8 p. 865 - 867

Precursor 1
87333-19-5
DownStream 0

HS Code	3004909090