N-(Azido-PEG3)-N-bis(PEG3-Boc)

Modify Date: 2024-02-07 23:02:14

N-(Azido-PEG3)-N-bis(PEG3-Boc) Structure
N-(Azido-PEG3)-N-bis(PEG3-Boc) structure
Common Name N-(Azido-PEG3)-N-bis(PEG3-Boc)
CAS Number 2055042-56-1 Molecular Weight 738.91
Density N/A Boiling Point N/A
Molecular Formula C34H66N4O13 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-(Azido-PEG3)-N-bis(PEG3-Boc)


N-(Azido-PEG3)-N-bis(PEG3-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-(Azido-PEG3)-N-bis(PEG3-Boc)

 N-(Azido-PEG3)-N-bis(PEG3-Boc) Biological Activity

Description N-(Azido-PEG3)-N-bis(PEG3-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C34H66N4O13
Molecular Weight 738.91

 Safety Information

Hazard Codes Xi