2112731-95-8

2112731-95-8 structure
2112731-95-8 structure
  • Name: N-(Azido-PEG3)-N-Boc-PEG4-acid
  • Chemical Name: N-(Azido-PEG3)-N-Boc-PEG4-acid
  • CAS Number: 2112731-95-8
  • Molecular Formula: C24H46N4O11
  • Molecular Weight: 566.64
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-04-13 15:58:30
  • Modify Date: 2024-01-12 10:57:58
  • N-(Azido-PEG3)-N-Boc-PEG4-acid is a PEG-based PROTAC linker with a terminal azide group and is used in the synthesis of PROTACs[1]

Name N-(Azido-PEG3)-N-Boc-PEG4-acid
Description N-(Azido-PEG3)-N-Boc-PEG4-acid is a PEG-based PROTAC linker with a terminal azide group and is used in the synthesis of PROTACs[1]
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Kanazaki K, et al. Feasibility of poly(ethylene glycol) derivatives as diagnostic drug carriers for tumor imaging. J Control Release. 2016 Mar 28;226:115-23.

Molecular Formula C24H46N4O11
Molecular Weight 566.64