2112731-51-6

2112731-51-6 structure
2112731-51-6 structure
  • Name: N-(Azido-PEG3)-N-Boc-PEG3-NHS ester
  • Chemical Name: N-(Azido-PEG3)-N-Boc-PEG3-NHS ester
  • CAS Number: 2112731-51-6
  • Molecular Formula: C26H45N5O12
  • Molecular Weight: 619.66
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 17:47:20
  • Modify Date: 2024-01-10 07:45:12
  • N-(Azido-PEG3)-N-Boc-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-(Azido-PEG3)-N-Boc-PEG3-NHS ester
Description N-(Azido-PEG3)-N-Boc-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C26H45N5O12
Molecular Weight 619.66