mHTT-IN-1

Modify Date: 2024-01-14 18:36:00

mHTT-IN-1 Structure
mHTT-IN-1 structure
Common Name mHTT-IN-1
CAS Number 2839311-21-4 Molecular Weight 381.45
Density N/A Boiling Point N/A
Molecular Formula C18H19N7OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of mHTT-IN-1


mHTT-IN-1 (Example 1) is a potent mutant huntingtin (mHTT) inhibitor. mHTT is toxic and a major cause of the inherited autosomal dominant neurodegenerative disorder, Huntington's disease (HD). mHTT-IN-1 conducts the reduction of mHTT with an EC50 value of 46 nM[1].

 Names

Name mHTT-IN-1

 mHTT-IN-1 Biological Activity

Description mHTT-IN-1 (Example 1) is a potent mutant huntingtin (mHTT) inhibitor. mHTT is toxic and a major cause of the inherited autosomal dominant neurodegenerative disorder, Huntington's disease (HD). mHTT-IN-1 conducts the reduction of mHTT with an EC50 value of 46 nM[1].
Related Catalog
References

[1]. Brom, et al. Preparation of thiazolopyrimidinone derivatives and uses thereof. World Intellectual Property Organization, WO2022194801 A1. 2022-09-22.

 Chemical & Physical Properties

Molecular Formula C18H19N7OS
Molecular Weight 381.45