2’-O-Methyl-4-thiouridine

Modify Date: 2024-04-03 18:12:38

2’-O-Methyl-4-thiouridine structure	Common Name	2’-O-Methyl-4-thiouridine
	CAS Number	34218-80-9	Molecular Weight	274.29
	Density	1.6±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₁₀H₁₄N₂O₅S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 2’-O-Methyl-4-thiouridine

2’-O-Methyl-4-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	1-(2-O-Methyl-β-D-ribofuranosyl)-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone
Synonym	More Synonyms

Description	2’-O-Methyl-4-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Density	1.6±0.1 g/cm3
Molecular Formula	C₁₀H₁₄N₂O₅S
Molecular Weight	274.29
Exact Mass	274.062347
LogP	0.00
Index of Refraction	1.664

1-(2-O-Methyl-β-D-ribofuranosyl)-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone

2(1H)-Pyrimidinone, 3,4-dihydro-1-(2-O-methyl-β-D-ribofuranosyl)-4-thioxo-

2’-O-Methyl-4-thiouridine

Use of 2’-O-Methyl-4-thiouridine

Names

2’-O-Methyl-4-thiouridine Biological Activity

Chemical & Physical Properties

Synonyms