5-Bromo-3’-deoxy-3’-fluorouridine

Modify Date: 2024-02-01 13:47:09

5-Bromo-3’-deoxy-3’-fluorouridine Structure
5-Bromo-3’-deoxy-3’-fluorouridine structure
Common Name 5-Bromo-3’-deoxy-3’-fluorouridine
CAS Number 439579-22-3 Molecular Weight 325.09
Density 2.0±0.1 g/cm3 Boiling Point N/A
Molecular Formula C9H10BrFN2O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5-Bromo-3’-deoxy-3’-fluorouridine


5-Bromo-3’-deoxy-3’-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 5-BroMo-3'-deoxy-3'-fluorouridine
Synonym More Synonyms

 5-Bromo-3’-deoxy-3’-fluorouridine Biological Activity

Description 5-Bromo-3’-deoxy-3’-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 2.0±0.1 g/cm3
Molecular Formula C9H10BrFN2O5
Molecular Weight 325.09
Exact Mass 323.975708
LogP -0.45
Index of Refraction 1.648

 Synonyms

5-Bromo-3'-deoxy-3'-fluorouridine
MFCD25542530
Uridine, 5-bromo-3'-deoxy-3'-fluoro-