2’-Deoxy-2’-iodouridine; 2’-Iodo-2’-deoxyuridine

Modify Date: 2024-01-02 23:14:08

2’-Deoxy-2’-iodouridine; 2’-Iodo-2’-deoxyuridine Structure
2’-Deoxy-2’-iodouridine; 2’-Iodo-2’-deoxyuridine structure
Common Name 2’-Deoxy-2’-iodouridine; 2’-Iodo-2’-deoxyuridine
CAS Number 4753-03-1 Molecular Weight 354.10
Density N/A Boiling Point N/A
Molecular Formula C9H11IN2O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2’-Deoxy-2’-iodouridine; 2’-Iodo-2’-deoxyuridine


2’-Deoxy-2’-iodouridine; 2’-Iodo-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-iodooxolan-2-yl]pyrimidine-2,4-dione
Synonym More Synonyms

  Biological Activity

Description 2’-Deoxy-2’-iodouridine; 2’-Iodo-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C9H11IN2O5
Molecular Weight 354.10
Exact Mass 353.97100
PSA 104.81000

 Synonyms

Uridine,2'-deoxy-2'-iodo
2'-deoxy-2'-iodouridine
Uridine,2'-deoxy-2'-iodo-(7CI,8CI,9CI)
2'-Iodo-2'-deoxyuridine