S-Me-DM4

Modify Date: 2024-04-06 20:20:33

S-Me-DM4 Structure
S-Me-DM4 structure
Common Name S-Me-DM4
CAS Number 890654-03-2 Molecular Weight 794.39
Density N/A Boiling Point N/A
Molecular Formula C39H56ClN3O10S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of S-Me-DM4


S-Me-DM4 is a metabolite of DM4 S-methylated by intracellular enzyme. DM4 (HY-100503) is a microtubule-depolymerizing maytansinoid with strong cytotoxicity. DM4 can be used as an ADC Cytotoxin molecule[1].

 Names

Name S-Me-DM4

 S-Me-DM4 Biological Activity

Description S-Me-DM4 is a metabolite of DM4 S-methylated by intracellular enzyme. DM4 (HY-100503) is a microtubule-depolymerizing maytansinoid with strong cytotoxicity. DM4 can be used as an ADC Cytotoxin molecule[1].
Related Catalog
References

[1]. Widdison W, et al. Metabolites of antibody-maytansinoid conjugates: characteristics and in vitro potencies. Mol Pharm. 2015 Jun 1;12(6):1762-73.  

 Chemical & Physical Properties

Molecular Formula C39H56ClN3O10S
Molecular Weight 794.39