2-Phenylethyl isothiocyanate-d5

Modify Date: 2024-01-22 18:46:45

2-Phenylethyl isothiocyanate-d5 structure	Common Name	2-Phenylethyl isothiocyanate-d5
	CAS Number	912627-98-6	Molecular Weight	168.27000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₉H₄D₅NS	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 2-Phenylethyl isothiocyanate-d5

2-Phenylethyl isothiocyanate-d5 isothiocyanate-d5 is the deuterium labeled 2-Phenylethyl isothiocyanate[1]. 2-Phenylethyl isothiocyanate is a potent antifungal agent. 2-Phenylethyl isothiocyanate significantly inhibited spore germination and mycelial growth of Alternaria alternata, with a MIC (minimum inhibitory concentration) of 1.22 mM. The antifungal effect of 2-Phenylethyl isothiocyanate against Alternaria alternata might be via reduction in toxin content and breakdown of cell membrane integrity[2][3].

Name	[phenyl-2H5]phenethyl isothiocyanate

Description	2-Phenylethyl isothiocyanate-d5 isothiocyanate-d5 is the deuterium labeled 2-Phenylethyl isothiocyanate[1]. 2-Phenylethyl isothiocyanate is a potent antifungal agent. 2-Phenylethyl isothiocyanate significantly inhibited spore germination and mycelial growth of Alternaria alternata, with a MIC (minimum inhibitory concentration) of 1.22 mM. The antifungal effect of 2-Phenylethyl isothiocyanate against Alternaria alternata might be via reduction in toxin content and breakdown of cell membrane integrity[2][3].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. B. J. Smith, et al. In vitro inhibition of soil microorganisms by 2-phenylethyl isothiocyanate. Plant Pathology. 4 October 2002;51(5):585-593. [3]. Zhang M, et al. 2-Phenylethyl Isothiocyanate Exerts Antifungal Activity against Alternaria alternata by Affecting Membrane Integrity and Mycotoxin Production. Toxins (Basel). 2020 Feb 1512(2):124.

Molecular Formula	C₉H₄D₅NS
Molecular Weight	168.27000
Exact Mass	168.07700
PSA	44.45000
LogP	2.33190

2-Phenylethyl isothiocyanate-d5

Use of 2-Phenylethyl isothiocyanate-d5

Names

2-Phenylethyl isothiocyanate-d5 Biological Activity

Chemical & Physical Properties