(R)-PD 0325901CL

Names

[ CAS No. ]:
1003216-77-0

[ Name ]:
(R)-PD 0325901CL

Biological Activity

[Description]:

(R)-PD 0325901CL is an isomer of PD 0325901CL. PD 0325901CL is a selective inhibitor of mitogen-activated protein kinase kinase (MEK) involved in cancer research. PD 0325901CL inhibits the growth of cancer cells in vitro and in vivo[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> MAPK/ERK Pathway >> MEK

[References]

[1]. Bain J, et al. The selectivity of protein kinase inhibitors: a further update. Biochem J. 2007 Dec 15;408(3):297-315.  

Chemical & Physical Properties

[ Molecular Formula ]:
C16H14ClF2IN2O4

[ Molecular Weight ]:
498.64800

[ Exact Mass ]:
497.96500

[ PSA ]:
94.31000

[ LogP ]:
3.62880

Related Compounds