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meta-METHOXYTOPOLIN RIBOSIDE (MemTR)

Names

[ CAS No. ]:
101565-95-1

[ Name ]:
meta-METHOXYTOPOLIN RIBOSIDE (MemTR)

[Synonym ]:
meta-methoxytopolin riboside

Biological Activity

[Description]:

N-[(3-Methoxyphenyl)methyl]adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

[2]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.  

Chemical & Physical Properties

[ Molecular Formula ]:
C18H21N5O5

[ Molecular Weight ]:
387.39

[ Exact Mass ]:
387.15400

[ PSA ]:
134.78000

[ LogP ]:
0.13150

Related Compounds