Palifosfamide tromethamine
Names
[ CAS No. ]:
1070409-31-2
[ Name ]:
Palifosfamide tromethamine
[Synonym ]:
ZIO-201-T
UNII-0X5A3C04ID
Palifosfamide tromethamine
Biological Activity
[Description]:
Palifosfamide (tromethamine) is a synthetic alkylating agent with potential antineoplastic activity. As the stabilized active metabolite of ifosfamide, palifosfamide (tromethamine) irreversibly alkylates and crosslinks DNA through GC base pairs. This leads to an inhibition of DNA replication and ultimately cell death. Compared to ifosfamide, palifosfamide (tromethamine) is less toxic.
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C8H22Cl2N3O5P
[ Molecular Weight ]:
342.15700
[ Exact Mass ]:
341.06700
[ PSA ]:
157.88000