2'-Deoxy-N6-phenoxyacetyladenosine

Names

[ Name ]:
2'-Deoxy-N6-phenoxyacetyladenosine

[Synonym ]:
N-phenoxyacetyl-2'-deoxyadenosine
2'-Deoxy-N6-phenoxyacetyladenosine
N6-phenoxyacetyl-2'-deoxyadenosine

Biological Activity

[Description]:

2'-Deoxy-N6-phenoxyacetyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
1.58±0.1 g/cm3(Predicted)

[ Molecular Formula ]:
C₁₈H₁₉N₅O₅

[ Molecular Weight ]:
385.37

[ Exact Mass ]:
385.13900

[ PSA ]:
131.62000

[ LogP ]:
0.55750

[ Storage condition ]:
-20℃

2'-Deoxy-N6-phenoxyacetyladenosine

Names

Biological Activity

Chemical & Physical Properties

MSDS

Click to get detail MSDS

Synthetic Route

Click to get detail synthetic route