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S-99

Names

[ CAS No. ]:
1124381-69-6

[ Name ]:
S-99

[Synonym ]:
N-[5-(Isopropylamino)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]nicotinamide
3-Pyridinecarboxamide, N-[5-[(1-methylethyl)amino]-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]-

Biological Activity

[Description]:

ASK1-IN-5 (S-99) is an inhibitor of apoptosis signal-regulated kinase 1 (ASK1) and is useful in the study of autoimmune and neurodegenerative diseases[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Inflammation/Immunology
Research Areas >> Neurological Disease
Signaling Pathways >> MAPK/ERK Pathway >> MAP3K

[References]

[1]. Dominique Swinnen, et al.Triazolopyridine compounds and their use as ask inhibitors.WO2009027283A1

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Molecular Formula ]:
C16H15F3N6O

[ Molecular Weight ]:
364.33

[ Exact Mass ]:
364.125946

[ LogP ]:
2.66

[ Index of Refraction ]:
1.631

[ Storage condition ]:
-20°C

Related Compounds