3-Azaspiro[5.5]undecane,hydrochloride (1:1)

Names

[ Name ]:
3-Azaspiro[5.5]undecane,hydrochloride (1:1)

[Synonym ]:
3-azaspiro[5.5]undecane,hydrochloride
EINECS 214-404-1

Biological Activity

[Description]:

3-Azaspiro[5.5]undecane (4,4-Pentamethylenepiperidine) hydrochloride is an inhibitor targeting the WT influenza A virus M2 (A/M2), with an IC50 of 1 μM[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Influenza Virus

Research Areas >> Infection

[Target]

IC50: 1 μM (influenza A virus M2)[1]

[References]

[1]. Wang J, et al. Exploring the Requirements for the Hydrophobic Scaffold and Polar Amine in inhibitors of M2 from Influenza A Virus. ACS Med Chem Lett. 2011 Apr 14;2(4):307-312.

Chemical & Physical Properties

[ Boiling Point ]:
273.7ºC at 760 mmHg

[ Molecular Formula ]:
C₁₀H₂₀ClN

[ Molecular Weight ]:
189.73

[ Flash Point ]:
119.3ºC

[ Exact Mass ]:
189.12800

[ PSA ]:
12.03000

[ LogP ]:
3.45110

[ Vapour Pressure ]:
0.00437mmHg at 25°C

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%