4-O-Methylepisappanol

Names

[ CAS No. ]:
112529-37-0

[ Name ]:
4-O-Methylepisappanol

[Synonym ]:
4-O-methylepisappanol

Biological Activity

[Description]:

4-O-Methylepisappanol (compound 9) is nature product that could be isolated from heartwood of Caesalpinia sappan. 4-O-Methylepisappanol is a potent neuraminidase inhibitor on the surface of influenza viruses with IC50 values of 42.8, 63.2, and 63.2 µM for A/Chicken/Korea/MS96/96 [H9N2], A/PR/8/34 [H1N1], and A/Hong Kong/8/68 [H3N2], respectively[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Influenza Virus
Research Areas >> Infection

[References]

[1]. Jeong HJ, et, al. Homoisoflavonoids from Caesalpinia sappan displaying viral neuraminidases inhibition. Biol Pharm Bull. 2012;35(5):786-90.  

Chemical & Physical Properties

[ Molecular Formula ]:
C17H18O6

[ Molecular Weight ]:
318.32100

[ Exact Mass ]:
318.11000

[ PSA ]:
99.38000

[ LogP ]:
1.85710

Precursor & DownStream

Precursor

DownStream


Related Compounds