2'-Deoxy-2'-fluoro-5-trifluoromethyl-arabinouridine

Names

[ CAS No. ]:
114652-80-1

[ Name ]:
2'-Deoxy-2'-fluoro-5-trifluoromethyl-arabinouridine

[Synonym ]:
1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-(trifluoromethyl)-2,4(1H,3H)-pyrimidinedione
2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-(trifluoromethyl)-
MFCD00877795

Biological Activity

[Description]:

2′-Deoxy-2′-fluoro-5-triflu oromethyl-arabinouridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93.  

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Molecular Formula ]:
C10H10F4N2O5

[ Molecular Weight ]:
314.19

[ Exact Mass ]:
314.052582

[ LogP ]:
0.46

[ Index of Refraction ]:
1.536

Related Compounds