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7-TFA-ap-7-Deaza-ddG

Names

[ CAS No. ]:
114748-68-4

[ Name ]:
7-TFA-ap-7-Deaza-ddG

[Synonym ]:
N-(3-{2-Amino-7-[(2R,5S)-5-(hydroxymethyl)tetrahydro-2-furanyl]-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl}-2-propyn-1-yl)-2,2,2-trifluoroacetamide
Acetamide, N-[3-[2-amino-4,7-dihydro-4-oxo-7-[(2R,5S)-tetrahydro-5-(hydroxymethyl)-2-furanyl]-3H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-propyn-1-yl]-2,2,2-trifluoro-

Biological Activity

[Description]:

7-TFA-ap-7-Deaza-ddG (compound 19d, US20060281100A1), a nucleotide derivative, can be used in the synthesis of thiotriphosphate nucleotide dye terminators which can be used in DNA sequencing reactions[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Shen G, et, al. Thiotriphosphate nucleotide dye terminators. US20060281100A1.

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Molecular Formula ]:
C16H16F3N5O4

[ Molecular Weight ]:
399.324

[ Exact Mass ]:
399.115448

[ LogP ]:
0.18

[ Index of Refraction ]:
1.657

[ Storage condition ]:
2-8℃

Related Compounds