3’-Deoxy-3’-fluoroinosine

Names

[ Name ]:
3’-Deoxy-3’-fluoroinosine

[Synonym ]:
3'-Deoxy-3'-fluoroinosine
Inosine, 3'-deoxy-3'-fluoro-

Biological Activity

[Description]:

3’-Deoxy-3’-fluoroinosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
2.0±0.1 g/cm3

[ Boiling Point ]:
682.1±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₀H₁₁FN₄O₄

[ Molecular Weight ]:
270.22

[ Flash Point ]:
366.3±34.3 °C

[ Exact Mass ]:
270.076447

[ LogP ]:
-0.79

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.810