cyprodinil

Names

[ Name ]:
cyprodinil

[Synonym ]:
Unix
4-cyclopropyl-6-methyl-N-phenyl-2-pyrimidineamine
4-Cyclopropyl-6-methyl-N-phenyl-2-pyrimidinamine
7813601
T6N CNJ BMR& D1 F- AL3TJ
MFCD01632330
2-Pyrimidinamine, 4-cyclopropyl-6-methyl-N-phenyl-
cyprodinil
2-phenylamino-4-cyclopropyl-6-methyl-pyrimidine
2-anilino-4-methyl-6-cyclopropylpyrimidine
4-Cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine
2-phenylamino-4-methyl-6-cyclopropylpyrimidine
4-Cyclopropyl-6-methyl-N-phenylpyrimidin-2-amin
Chorus 75WG
2-Pyrimidinamine,4-cyclopropyl-6-methyl-N-phenyl

Biological Activity

[Description]:

Cyprodinil is an anilinopyrimidine broad-spectrum fungicide that inhibits the biosynthesis of methionine in phytopathogenic fungi. Cyprodinil inhibits mycelial cell growth of B. cinerea, P. herpotrichoides, and H. oryzae on amino acid-free media (IC50s=0.44, 4.8, and 0.03 µM, respectively). Cyprodinil acts as an androgen receptor (AR) agonist (EC50=1.91 µM) in the absence of the AR agonist DHT and inhibits the androgenic effect of DHT (IC50=15.1 µM).

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Fungal

Signaling Pathways >> Others >> Androgen Receptor

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
406.0±48.0 °C at 760 mmHg

[ Melting Point ]:
68 - 70ºC

[ Molecular Formula ]:
C₁₄H₁₅N₃

[ Molecular Weight ]:
225.289

[ Flash Point ]:
199.3±29.6 °C

[ Exact Mass ]:
225.126602

[ PSA ]:
37.81000

[ LogP ]:
4.00

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.659

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H317-H319-H410

[ Precautionary Statements ]:
P273-P280-P305 + P351 + P338-P333 + P313-P391-P501

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/38;R43

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
UN 3077

[ Packaging Group ]:
III

[ HS Code ]:
2942000000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2942000000

Articles

Degradation of cyprodinil, fludioxonil, cyfluthrin and pymetrozine on lettuce after different application methods.

J. Environ. Sci. Health B 42(7) , 761-6, (2007)

Degradation of two fungicides (cyprodinil and fludioxonil) and two insecticides (cyfluthrin and pymetrozine) applied on iceberg and romaine lettuce under field conditions with different methods (porta...

Molecular characterization, fitness and mycotoxin production of benzimidazole-resistant isolates of Penicillium expansum.

Int. J. Food Microbiol. 162(3) , 237-44, (2013)

Penicillium expansum field-strains resistant to benzimidazole fungicides were isolated in high frequency from decayed apple fruit collected from packinghouses and processing industries located in the ...

Influence of the adjuvants in a commercial formulation of the fungicide "Switch" on the adsorption of their active ingredients: cyprodinil and fludioxonil, on soils devoted to vineyard.

J. Hazard. Mater. 193 , 288-95, (2011)

The objective of this work was to assess the effect of adjuvants in the sorption in soils of the fungicides, cyprodinil and fludioxonil, usually applied together in a mixture commonly called 'Switch'....