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N4-Benzoyl-7'-OH-N-trityl Morpholino cytosine

Names

[ CAS No. ]:
125515-31-3

[ Name ]:
N4-Benzoyl-7'-OH-N-trityl Morpholino cytosine

[Synonym ]:
MFCD22666302
Benzamide, N-[1,2-dihydro-1-[(2R,6S)-6-(hydroxymethyl)-4-(triphenylmethyl)-2-morpholinyl]-2-oxo-4-pyrimidinyl]-
N-{1-[(2R,6S)-6-(Hydroxymethyl)-4-trityl-2-morpholinyl]-2-oxo-1,2-dihydro-4-pyrimidinyl}benzamide

Biological Activity

[Description]:

N4-Benzoyl-7’-OH-N-trityl morpholino cytosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Molecular Formula ]:
C35H32N4O4

[ Molecular Weight ]:
572.65

[ Exact Mass ]:
572.242371

[ LogP ]:
5.28

[ Index of Refraction ]:
1.649

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds