KBR2738

Names

[ Name ]:
KBR2738

[Synonym ]:
MFCD03095700
2’,3’-dichloro-4’-hydroxy-1-methylcyclohexanecarboxanilide
N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide
EINECS 422-530-5
Fenhexamid
N-(2,3-Dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide
Cyclohexanecarboxamide, N-(2,3-dichloro-4-hydroxyphenyl)-1-methyl-
KBR2738
KBR-2738
L6TJ AVMR DQ BG CG& A1

Biological Activity

[Description]:

Fenhexamid, a botryticide, is a sterol biosynthesis inhibitor. Fenhexamid shows fungicide efficient against the plant pathogenic fungus Botryotinia fuckeliana (Botrytis cinerea)[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

[References]

[1]. Debieu D, et al. The hydroxyanilide fenhexamid, a new sterol biosynthesis inhibitor fungicide efficient against the plant pathogenic fungus Botryotinia fuckeliana (Botrytis cinerea). Pest Manag Sci. 2001 Nov;57(11):1060-7.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
457.9±45.0 °C at 760 mmHg

[ Melting Point ]:
153ºC

[ Molecular Formula ]:
C₁₄H₁₇Cl₂NO₂

[ Molecular Weight ]:
302.20

[ Flash Point ]:
230.7±28.7 °C

[ Exact Mass ]:
301.063629

[ PSA ]:
49.33000

[ LogP ]:
4.02

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.604

Safety Information

[ Symbol ]:

GHS09

[ Hazard Statements ]:
H411

[ Precautionary Statements ]:
P273-P391-P501

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Risk Phrases ]:
R51/53

[ Safety Phrases ]:
S61

[ RIDADR ]:
UN 3077 9/PG 3

[ RTECS ]:
GU7879550

Articles

Simultaneous determination of sixteen amide fungicides in vegetables and fruits by dispersive solid phase extraction and liquid chromatography-tandem mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 989 , 11-20, (2015)

A modified quick, easy, cheap, effective, rugged, and safe (QuEChERS) method using multi-walled carbon nanotubes (MWCNTs) as a reversed-dispersive solid phase extraction (r-dSPE) material combined wit...

The effects of the fungicides fenhexamid and myclobutanil on SH-SY5Y and U-251 MG human cell lines.

Environ. Toxicol. Pharmacol. 38(3) , 968-76, (2014)

Mixtures of pesticides in foodstuffs and the environment are ubiquitous in the developed world and although agents are usually exhaustively tested individually, the toxicological implications of pesti...

Fungicide-driven evolution and molecular basis of multidrug resistance in field populations of the grey mould fungus Botrytis cinerea.

PLoS Pathog. 5 , e1000696, (2009)

The grey mould fungus Botrytis cinerea causes losses of commercially important fruits, vegetables and ornamentals worldwide. Fungicide treatments are effective for disease control, but bear the risk o...