CHK-IN-1

Names

[ CAS No. ]:
1278405-51-8

[ Name ]:
CHK-IN-1

[Description]:

CHK-IN-1 is an inhibitor of CHK1 and CHK2, with anti-proliferative activities.

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Checkpoint Kinase (Chk)

Research Areas >> Cancer

[Target]

Chk1

Chk2

[In Vitro]

CHK-IN-1 can prevent DNA damage repair mechanism from arresting the cell cycle at the G2/M checkpoint[1].

[References]

[Related Small Molecules]

LY2606368 | AZD7762 | CCT245737 | LY2603618 | CCT241533 hydrochloride | MK-8776(SCH 900776) | CHIR-124 | CHK2 INHIBITOR II | PF-477736 | CCT244747 | GDC-0575(ARRY-575) | CHK1 inhibitor | CHK1-IN-2

[ Molecular Formula ]:
C₁₈H₁₉ClFN₅OS

[ Molecular Weight ]:
407.89