(+)-CBI-CDPI1

Names

[ CAS No. ]:
128300-14-1

[ Name ]:
(+)-CBI-CDPI1

Biological Activity

[Description]:

(+)-CBI-CDPI1 is an enhanced functional analog of CC-1065. (+)-CBI-CDPI1 is a DNA alkylating agent. (+)-CBI-CDPI1 is an antibody drug conjugates (ADCs) toxin.

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Cytotoxin
Signaling Pathways >> Cell Cycle/DNA Damage >> DNA Alkylator/Crosslinker

[References]

[1]. Boger DL, et al. Molecular basis for sequence selective DNA alkylation by (+)- and ent-(-)-CC-1065 and related agents: alkylation site models that accommodate the offset AT-rich adenine N3 alkylation selectivity. Bioorg Med Chem. 1994 Feb;2(2):115-35.

Chemical & Physical Properties

[ Molecular Formula ]:
C25H20N4O3

[ Molecular Weight ]:
424.45

Related Compounds