Asperfuran

Names

[ Name ]:
Asperfuran

[Synonym ]:
5,7-Benzofurandiol,2,3-dihydro-2-(1E,3E)-1,3-pentadien-1-yl-,(2R)
3-(penta-1,2-dien-1-yl)-2,3-dihydro-1-benzofuran-5,7-diol
5,7-Benzofurandiol,2,3-dihydro-2-(1,3-pentadienyl)-,(R-(E,E))
(-)-arthrographol

Biological Activity

[Description]:

Asperfuran is an antifungal dihydrobenzofuran derivative produced by a strain of Aspergillus oryzae. Asperfuran weakly inhibits chitin synthase from Coprinus cinereus. Asperfuran shows weak cytotoxicity In HeLa S3 and L1210 cells with an IC50 of 25 μg/ml[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

[References]

[1]. Pfefferle W, et al. Asperfuran, a novel antifungal metabolite from Aspergillus oryzae. J Antibiot (Tokyo). 1990;43(6):648-654.

Chemical & Physical Properties

[ Density]:
1.254g/cm3

[ Boiling Point ]:
380.7ºC at 760mmHg

[ Molecular Formula ]:
C₁₃H₁₄O₃

[ Molecular Weight ]:
218.24800

[ Flash Point ]:
184ºC

[ Exact Mass ]:
218.09400

[ PSA ]:
49.69000

[ LogP ]:
2.53360

[ Vapour Pressure ]:
2.44E-06mmHg at 25°C

[ Index of Refraction ]:
1.659

Safety Information

[ HS Code ]:
2932999099

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%