famoxadone

Names

[ Name ]:
famoxadone

[Synonym ]:
5-Methyl-5-(4-phenoxyphenyl)-3-(phenylamino)-1,3-oxazolidine-2,4-dione
(RS)-3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione
3-Anilino-5-methyl-5-(4-phenoxyphenyl)oxazolidine-2,4-dione
MFCD03427409
rac-(5R)-3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione
T5OVNV EHJ CMR& E1 ER DOR
Famoxate
2,4-Oxazolidinedione, 5-methyl-5-(4-phenoxyphenyl)-3-(phenylamino)-
DPX-JE 874
famoxadone
3-Anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione
5-methyl-5-(4-phenoxyphenyl)-3-(phenylamino)-2,4-oxazolidinedione
EINECS 200-835-2
Famoxadon

Biological Activity

[Description]:

Famoxadone (DPX-JE874) is a fungicide acting against a broad spectrum of fungi and is widely used in Integrated Pest Management strategies in different agricultural crops[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

[References]

[1]. D T Likas, et al. Rapid Gas Chromatographic Method for the Determination of Famoxadone, Trifloxystrobin and Fenhexamid Residues in Tomato, Grape and Wine Samples. J Chromatogr A. 2007 May 25;1150(1-2):208-14.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
491.3±55.0 °C at 760 mmHg

[ Melting Point ]:
140.3-141.8ºC

[ Molecular Formula ]:
C₂₂H₁₈N₂O₄

[ Molecular Weight ]:
374.389

[ Flash Point ]:
250.9±31.5 °C

[ Exact Mass ]:
374.126648

[ PSA ]:
67.87000

[ LogP ]:
4.76

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.659

[ Storage condition ]:
0-6°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H302-H312-H319-H332

[ Precautionary Statements ]:
P210-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn,N,F

[ Risk Phrases ]:
R48/22

[ Safety Phrases ]:
S46

[ RIDADR ]:
UN1648 3/PG 2

[ Hazard Class ]:
9.0

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Development and validation of one-step ultrasound-assisted extraction for simultaneous determination of multiclass fungicides in soils.

J. AOAC Int. 98(1) , 192-200, (2015)

A rapid, efficient, and simple one-step ultrasound-assisted extraction (UAE) method was developed for the analysis of seven fungicides (cymoxanil, metalaxyl, mandipropamid, folpet, chlorothalonil, kre...

Triplet state of the semiquinone-Rieske cluster as an intermediate of electronic bifurcation catalyzed by cytochrome bc1.

Biochemistry 52 , 6388-95, (2013)

Efficient energy conversion often requires stabilization of one-electron intermediates within catalytic sites of redox enzymes. While quinol oxidoreductases are known to stabilize semiquinones, one of...