2-(6-amino-8-methylamino-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

Names

[ Name ]:
2-(6-amino-8-methylamino-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

[Synonym ]:
n8-methyl-9-pentofuranosyl-9h-purine-6,8-diamine
8-methylamino-adenosine

Biological Activity

[Description]:

8-(Methylamino)adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₁H₁₆N₆O₄

[ Molecular Weight ]:
296.28

[ Exact Mass ]:
296.12300

[ PSA ]:
154.80000

2-(6-amino-8-methylamino-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

Names

Biological Activity

Chemical & Physical Properties

Related Compounds