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2-Amino-9-[(2,3,5-tri-O-benzoyl-2-C-Methyl-β-D-ribofuranosyl)]-9H-purine

Names

[ CAS No. ]:
1345969-99-4

[ Name ]:
2-Amino-9-[(2,3,5-tri-O-benzoyl-2-C-Methyl-β-D-ribofuranosyl)]-9H-purine

[Synonym ]:
9H-Purin-2-amine, 9-(2,3,5-tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)-
MFCD25542505
9-(2,3,5-Tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)-9H-purin-2-amine

Biological Activity

[Description]:

9-(2,3,5-Tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)-9H-purin-2-amine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
797.7±70.0 °C at 760 mmHg

[ Molecular Formula ]:
C32H27N5O7

[ Molecular Weight ]:
593.59

[ Flash Point ]:
436.2±35.7 °C

[ Exact Mass ]:
593.191040

[ LogP ]:
7.04

[ Vapour Pressure ]:
0.0±2.8 mmHg at 25°C

[ Index of Refraction ]:
1.678

Related Compounds